呼肠孤病毒信使核糖核酸中5'末端非编码序列的异质性
5' Terminal noncoding sequence heterogeneity in reovirus mRNA.
作者信息
Hastings K E, Millward S
出版信息
Nucleic Acids Res. 1977 Jan;4(1):195-205. doi: 10.1093/nar/4.1.195.
Abstract
The nucleotide sequences of the mRNAs of reovirus appear to diverge near the 5' termini. Ribonuclease T1 digestion of methylated mRNA synthesized in vitro yielded seven different 5' terminal fragments of the form m7G5'pp5' GmpCpUp(Np)nGp. Chain length analysis showed that the parameter "n" in this structural formula assumes the values 3, 4 and 5.
摘要
呼肠孤病毒mRNA的核苷酸序列似乎在5'末端附近出现分歧。对体外合成的甲基化mRNA进行核糖核酸酶T1消化，产生了七种不同的5'末端片段，其形式为m7G5'pp5' GmpCpUp(Np)nGp。链长分析表明，该结构式中的参数“n”取值为3、4和5。
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