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相似文献

1
Proflavine sensitivity of RNA processing in isolated nuclei.分离细胞核中RNA加工的原黄素敏感性。
Nucleic Acids Res. 1977 Mar;4(3):503-11. doi: 10.1093/nar/4.3.503.
2
Cytosol-modulated transport of messenger RNA from isolated nuclei.胞质溶胶调节的信使核糖核酸从分离细胞核的转运
Cancer Res. 1973 Aug;33(8):1821-8.
3
Studies on transcription termination and splicing of the rRNA precursor in vivo in the presence of proflavine.在原黄素存在的情况下对体内rRNA前体转录终止和剪接的研究。
Nucleic Acids Res. 1984 Jan 25;12(2):873-86. doi: 10.1093/nar/12.2.873.
4
Transport of informosomes from isolated nuclei of regenerating rat liver.信息体从再生大鼠肝脏分离细胞核的转运
Biochem Biophys Res Commun. 1972 Sep 5;48(5):1259-65. doi: 10.1016/0006-291x(72)90847-9.
5
Stabilization of adenovirus nuclear RNA by intercalating drugs.通过嵌入药物稳定腺病毒核RNA。
Biochim Biophys Acta. 1978 Sep 27;520(2):404-10. doi: 10.1016/0005-2787(78)90237-x.
6
Insulin-modulated transport of RNA from isolated live nuclei.胰岛素调节的RNA从分离的活细胞核的转运。
Arch Biochem Biophys. 1981 Aug;210(1):275-9. doi: 10.1016/0003-9861(81)90190-9.
7
[Molecular mechanisms of inhibition of RNA synthesis. DNA-interacting inhibitors].[RNA合成抑制的分子机制。DNA相互作用抑制剂]
Postepy Biochem. 1985;31(1):53-86.
8
Processing and release of ribosomal RNA from isolated nuclei: analysis of the ATP-dependence and cytosol-dependence.从分离的细胞核中加工和释放核糖体RNA：对ATP依赖性和胞质溶胶依赖性的分析。
Eur J Biochem. 1974 Nov 1;49(1):93-100. doi: 10.1111/j.1432-1033.1974.tb03814.x.
9
Regulated transport of ribosomal subunits from regenerating rat liver nuclei in a cell-free system.无细胞体系中大鼠再生肝细胞核核糖体亚基的调控转运
Cancer Res. 1972 Nov;32(11):2314-21.
10
Age-dependence of nuclear RNA processing.核RNA加工的年龄依赖性。
Mech Ageing Dev. 1977 Jul-Aug;6(4):259-64. doi: 10.1016/0047-6374(77)90026-4.

引用本文的文献

1
In vitro splicing of the ribosomal RNA precursor in isolated nucleoli from Tetrahymena.嗜热四膜虫分离核仁中核糖体RNA前体的体外剪接
Nucleic Acids Res. 1980 Dec 11;8(23):5551-66. doi: 10.1093/nar/8.23.5551.
2
Studies on transcription termination and splicing of the rRNA precursor in vivo in the presence of proflavine.在原黄素存在的情况下对体内rRNA前体转录终止和剪接的研究。
Nucleic Acids Res. 1984 Jan 25;12(2):873-86. doi: 10.1093/nar/12.2.873.
3
An assessment of some methodological criticisms of studies of RNA efflux from isolated nuclei.对关于从分离细胞核中RNA流出研究的一些方法学批评的评估。
Biochem J. 1983 Sep 15;214(3):915-21. doi: 10.1042/bj2140915.
4
Heterogeneous nuclear RNA promotes synthesis of (2',5')oligoadenylate and is cleaved by the (2',5')oligoadenylate-activated endoribonuclease.不均一核RNA促进（2′，5′）寡腺苷酸的合成，并被（2′，5′）寡腺苷酸激活的核糖核酸内切酶切割。
Mol Cell Biol. 1982 Feb;2(2):154-60. doi: 10.1128/mcb.2.2.154-160.1982.
5
Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression.c-myc基因表达过程中，第一外显子内的转录停滞是一种快速调控机制。
Nucleic Acids Res. 1986 Nov 11;14(21):8331-46. doi: 10.1093/nar/14.21.8331.
6
Active transport of messenger ribonucleoprotein particles in a reconstituted cell-free system.信使核糖核蛋白颗粒在重构无细胞系统中的主动运输。
Proc Natl Acad Sci U S A. 1987 Aug;84(15):5163-6. doi: 10.1073/pnas.84.15.5163.
7
Cleavage of pre-mRNA sequences by ribonucleases bound to nuclear RNP particles of rat liver.核糖核酸酶与大鼠肝脏核核糖核蛋白颗粒结合对前体信使核糖核酸序列的切割
Mol Biol Rep. 1978 Oct 16;4(3):157-61. doi: 10.1007/BF00777517.
8
Effects of ethidium bromide on the production of ribosomal RNA in cultured mouse cells.溴化乙锭对培养的小鼠细胞中核糖体RNA产生的影响。
Nucleic Acids Res. 1979 Jun 25;6(8):2863-77. doi: 10.1093/nar/6.8.2863.

本文引用的文献

1
Methylation of 45 s ribosomal RNA precursor in HeLa cells.HeLa细胞中45s核糖体RNA前体的甲基化
J Mol Biol. 1967 Jan 28;23(2):149-61. doi: 10.1016/s0022-2836(67)80023-8.
2
Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA.聚腺苷酸序列：在核RNA转变为信使RNA过程中的作用
Science. 1971 Oct 29;174(4008):507-10. doi: 10.1126/science.174.4008.507.
3
Transport of informosomes from isolated nuclei of regenerating rat liver.信息体从再生大鼠肝脏分离细胞核的转运
Biochem Biophys Res Commun. 1972 Sep 5;48(5):1259-65. doi: 10.1016/0006-291x(72)90847-9.
4
Regulation of ribosome formation in regenerating rat liver.再生大鼠肝脏中核糖体形成的调控
Eur J Biochem. 1972 May;27(1):136-44. doi: 10.1111/j.1432-1033.1972.tb01819.x.
5
The isolation of messenger RNA from mammalian cells.从哺乳动物细胞中分离信使核糖核酸。
Methods Enzymol. 1974;30:605-12. doi: 10.1016/0076-6879(74)30058-4.
6
Stabilization of heterogeneous nuclear RNA by intercalating drugs.通过嵌入药物使不均一核RNA稳定。
Biochem Biophys Res Commun. 1973 Jun 8;52(3):928-34. doi: 10.1016/0006-291x(73)91026-7.
7
Eukaryotic messenger RNA.真核生物信使核糖核酸
Annu Rev Biochem. 1974;43(0):621-42. doi: 10.1146/annurev.bi.43.070174.003201.
8
Modified messenger ribonucleic acid release from isolated hepatic nuclei after inhibition of polyadenylate formation.多聚腺苷酸形成受抑制后，从分离的肝细胞核中释放出的修饰信使核糖核酸
Biochem J. 1974 Apr;139(1):191-6. doi: 10.1042/bj1390191.
9
Double-stranded regions in heterogeneous nuclear RNA from Hela cells.来自海拉细胞的不均一核RNA中的双链区域。
Proc Natl Acad Sci U S A. 1972 Sep;69(9):2537-41. doi: 10.1073/pnas.69.9.2537.
10
The in vivo equivalence of a cell-free system for RNA processing and transport.用于RNA加工和转运的无细胞系统的体内等效性。
Biochem Biophys Res Commun. 1974 May 20;58(2):354-60. doi: 10.1016/0006-291x(74)90372-6.

分离细胞核中RNA加工的原黄素敏感性。

Proflavine sensitivity of RNA processing in isolated nuclei.

作者信息

Yannarell A, Niemann M, Schumm D E, Webb T E

出版信息

Nucleic Acids Res. 1977 Mar;4(3):503-11. doi: 10.1093/nar/4.3.503.

DOI:10.1093/nar/4.3.503
PMID:866181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC342457/
Abstract

The intercalating agent proflavine inhibits the processing and subsequent release of preformed messenger RNA and ribosomal RNA from isolated liver nuclei to surrogate cytoplasm. The direct effect of proflavine on these processes, as monitored in a reconstituted cell-free system, supports the theory that base-paired segments (i.e. hairpin loops) in the precursor RNA's are involved as recognition sites in nuclear RNA processing.

摘要

嵌入剂原黄素可抑制从分离的肝细胞核到替代细胞质的预制信使核糖核酸和核糖体核糖核酸的加工及随后的释放。在重构的无细胞系统中监测到的原黄素对这些过程的直接作用，支持了前体核糖核酸中的碱基配对片段（即发夹环）作为核核糖核酸加工中的识别位点的理论。