Walter L, Fischer K, Günther E
Division of Immunogenetics, University of Göttingen, Gosslerstr. 12 d, D-37073 Göttingen, Germany.
Immunogenetics. 1996;44(3):218-21. doi: 10.1007/BF02602588.
A contig of cosmids containing the Ring1, Ring2, Ke6, Ke4, Rxrb, and Col11a2 genes in the rat major histocompatibility complex has been established and aligned to the class II cluster (RT1.Hb). The relative order and the transcriptional orientations of these rat genes are the same as in their human and mouse homologues. The distances are also similar, except for the Col11a2 - class II interval, which is clearly shorter in rat and mouse compared with human. The previously defined Ke5 probe could be shown to map into the large Col11a2 gene.
已构建出一个包含大鼠主要组织相容性复合体中Ring1、Ring2、Ke6、Ke4、Rxrb和Col11a2基因的黏粒重叠群，并将其与II类基因簇（RT1.Hb）比对。这些大鼠基因的相对顺序和转录方向与其人类和小鼠同源基因相同。除了Col11a2与II类基因之间的间隔外，距离也相似，与人类相比，大鼠和小鼠中的该间隔明显更短。先前定义的Ke5探针可定位到大型Col11a2基因中。
