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血小板保存V. 新鲜和冷冻保存的人血小板的存活、5-羟色胺摄取速度及对低渗应激的反应

Platelet preservation V. Survival, serotonin uptake velocity, and response to hypotonic stress of fresh and cryopreserved human platelets.

作者信息

Odink J, Brank A

出版信息

Transfusion. 1977 May-Jun;17(3):203-9. doi: 10.1046/j.1537-2995.1977.17377196351.x.

DOI:10.1046/j.1537-2995.1977.17377196351.x
PMID:867458
Abstract

The survival in vivo of 51Cr-labeled autologous human platelets, the serotonin uptake velocity, and the response to hypotonic stress were determined both before and after cryopreservation. Changes in platelet survival corresponded to changes in serotonin uptake velocity and response to hypotonic stress. No correlation was observed between the values of the survivla in vivo, the serotonin uptake velocity, and the response to hypotonic stress within the separate suspensions of fresh and cryopreserved platelets. There was no indication that hypercoagulability was induced by infusion of small amounts of cryopreserved platelets.

摘要

在冷冻保存前后分别测定了51Cr标记的自体人血小板在体内的存活率、血清素摄取速度以及对低渗应激的反应。血小板存活率的变化与血清素摄取速度和对低渗应激的反应变化相对应。在新鲜血小板和冷冻保存血小板的单独悬液中,未观察到体内存活率、血清素摄取速度和对低渗应激反应的值之间存在相关性。没有迹象表明输注少量冷冻保存的血小板会诱导高凝状态。

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Transfusion. 1977 May-Jun;17(3):203-9. doi: 10.1046/j.1537-2995.1977.17377196351.x.
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Characterization of procoagulant extracellular vesicles and platelet membrane disintegration in DMSO-cryopreserved platelets.二甲基亚砜冻存血小板中外源性促凝囊泡的特征及血小板膜解体。
J Extracell Vesicles. 2016 May 4;5:30422. doi: 10.3402/jev.v5.30422. eCollection 2016.
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Morphological and functional disturbances of platelets induced by cryopreservation.
冷冻保存诱导的血小板形态和功能紊乱。
J Clin Pathol. 1982 Aug;35(8):870-4. doi: 10.1136/jcp.35.8.870.
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Cryopreservation of platelets: an in-vitro comparison of four methods.血小板的冷冻保存:四种方法的体外比较
J Clin Pathol. 1981 Jan;34(1):71-5. doi: 10.1136/jcp.34.1.71.
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Survival in vivo of platelets stored for 48 hours in the buffycoat at 4 degrees C compared to platelet rich plasma stored at 22 degrees C.将在4℃白膜层中储存48小时的血小板与在22℃储存的富血小板血浆相比,其在体内的存活率。
Blut. 1987 Apr;54(4):201-6. doi: 10.1007/BF00594194.