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Drug resistance in cytomegalovirus: current knowledge and implications for patient management.

出版信息

J Acquir Immune Defic Syndr Hum Retrovirol. 1996;12 Suppl 1:S1-22.

PMID:8680897
Abstract
摘要

相似文献

1
Drug resistance in cytomegalovirus: current knowledge and implications for patient management.
J Acquir Immune Defic Syndr Hum Retrovirol. 1996;12 Suppl 1:S1-22.
2
[Strains of ganciclovir-resistant cytomegalovirus].耐更昔洛韦的巨细胞病毒毒株
Enferm Infecc Microbiol Clin. 1999 Aug-Sep;17(7):330-4.
3
Four dually resistant human cytomegalovirus strains from AIDS patients: single mutations in UL97 and UL54 open reading frames are responsible for ganciclovir- and foscarnet-specific resistance, respectively.来自艾滋病患者的四株双重耐药人巨细胞病毒毒株：UL97和UL54开放阅读框中的单突变分别导致对更昔洛韦和膦甲酸钠的特异性耐药。
Scand J Infect Dis Suppl. 1995;99:103-4.
4
Ganciclovir prophylaxis for CMV disease infrequently associated with viral resistance.
AIDS Patient Care. 1995 Dec;9(6):308.
5
Comprehensive restriction analysis of the UL97 region allows early detection of ganciclovir-resistant human cytomegalovirus in an immunocompromised child.对UL97区域进行全面的限制性分析可在一名免疫功能低下儿童中早期检测出对更昔洛韦耐药的人巨细胞病毒。
J Infect Dis. 1999 Aug;180(2):491-5. doi: 10.1086/314877.
6
CMV resistance: "more complicated than we thought".
J Int Assoc Physicians AIDS Care. 1996 May;2(5):37-9.
7
Emergence of a ganciclovir-resistant human cytomegalovirus strain with a new UL97 mutation in an AIDS patient.
AIDS. 1998 May 7;12(7):816-8.
8
Lack of emergence of cytomegalovirus UL97 mutations conferring ganciclovir (GCV) resistance following preemptive GCV therapy in allogeneic stem cell transplant recipients.在异基因干细胞移植受者中，抢先使用更昔洛韦（GCV）治疗后，未出现赋予GCV耐药性的巨细胞病毒UL97突变。
Antimicrob Agents Chemother. 2001 Dec;45(12):3669-71. doi: 10.1128/AAC.45.12.3669-3671.2001.
9
Foscarnet therapy of ganciclovir-resistant cytomegalovirus in marrow transplantation.
Transplantation. 1991 Jul;52(1):155-7.
10
Cytomegalovirus UL97 mutations associated with ganciclovir resistance in immunocompromised patients from Argentina.阿根廷免疫功能低下患者中与更昔洛韦耐药相关的巨细胞病毒UL97突变
J Clin Virol. 2004 Jul;30(3):271-5. doi: 10.1016/j.jcv.2003.11.003.

引用本文的文献

1
Evaluating phenotype and genotype of drug-resistant strains in herpesviruses.
Mol Biotechnol. 2001 Jun;18(2):155-67. doi: 10.1385/mb:18:2:155.
2
Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: inhibition of PI3-K activity inhibits viral replication and virus-induced signaling.人巨细胞病毒上调磷脂酰肌醇3激酶（PI3-K）信号通路：抑制PI3-K活性可抑制病毒复制及病毒诱导的信号传导。
J Virol. 2001 Jul;75(13):6022-32. doi: 10.1128/JVI.75.13.6022-6032.2001.
3
Interstrain variation in the human cytomegalovirus DNA polymerase sequence and its effect on genotypic diagnosis of antiviral drug resistance. Adult AIDS Clinical Trials Group CMV Laboratories.人巨细胞病毒DNA聚合酶序列的株间变异及其对抗病毒药物耐药性基因分型诊断的影响。成人艾滋病临床试验组巨细胞病毒实验室。
Antimicrob Agents Chemother. 1999 Jun;43(6):1500-2. doi: 10.1128/AAC.43.6.1500.
4
Resistance of human cytomegalovirus to antiviral drugs.人巨细胞病毒对抗病毒药物的耐药性。
Clin Microbiol Rev. 1999 Apr;12(2):286-97. doi: 10.1128/CMR.12.2.286.
5
Rapid ganciclovir susceptibility assay using flow cytometry for human cytomegalovirus clinical isolates.使用流式细胞术对人巨细胞病毒临床分离株进行更昔洛韦快速药敏试验。
Antimicrob Agents Chemother. 1998 Sep;42(9):2326-31. doi: 10.1128/AAC.42.9.2326.
6
Flow cytometric determination of ganciclovir susceptibilities of human cytomegalovirus clinical isolates.人巨细胞病毒临床分离株更昔洛韦敏感性的流式细胞术测定
J Clin Microbiol. 1998 Apr;36(4):958-64. doi: 10.1128/JCM.36.4.958-964.1998.
7
The Cys607-->Tyr change in the UL97 phosphotransferase confers ganciclovir resistance to two human cytomegalovirus strains recovered from two immunocompromised patients.UL97磷酸转移酶中Cys607突变为Tyr的变化，使从两名免疫功能低下患者体内分离出的两株人巨细胞病毒对更昔洛韦产生耐药性。
Antimicrob Agents Chemother. 1998 Feb;42(2):444-6. doi: 10.1128/AAC.42.2.444.
8
What clinicians need to know about antiviral drugs and viral resistance.临床医生需要了解的关于抗病毒药物和病毒耐药性的知识。
Infect Dis Clin North Am. 1997 Dec;11(4):945-67. doi: 10.1016/s0891-5520(05)70399-8.