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海洋天然产物研究:当前方向与未来潜力。

Marine natural products research: current directions and future potential.

作者信息

König G M, Wright A D

机构信息

Institute for Pharmaceutical Biology, Technical University of Braunschweig, Germany.

出版信息

Planta Med. 1996 Jun;62(3):193-211. doi: 10.1055/s-2006-957861.

DOI:10.1055/s-2006-957861
PMID:8693030
Abstract

Natural products research is increasingly turning to marine animals, plants, and microbes as source organisms. Several marine natural products are currently in preclinical and clinical evaluation, others show promising biological activities in in vitro and in vivo assays. Investigations of biological and chemical ecological phenomena in the marine world will contribute to a better understanding of marine habitats, and also provide a more founded basis regarding the search for pharmaceutically useful marine natural products.

摘要

天然产物研究越来越多地将海洋动物、植物和微生物作为来源生物。目前有几种海洋天然产物正处于临床前和临床评估阶段,其他一些在体外和体内试验中显示出有前景的生物活性。对海洋世界中生物和化学生态现象的研究将有助于更好地理解海洋栖息地,也为寻找具有药用价值的海洋天然产物提供更有根据的基础。

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