Likhoded V G, Anikhovskaia I A, Apollonin A V, Kozlova N N, Kudriavtsev A E, Khabriev R U, Iushchuk N D, Iakovlev M Iu
Zh Mikrobiol Epidemiol Immunobiol. 1996 Mar-Apr(2):76-9.
The treatment of thin blood smears with antibodies to glycolipid of chemotype Re, conjugated with horseradish peroxidase, revealed that under physiological conditions about 3.5% of leukocytes bound endotoxin of gram-negative bacteria by means of the Fc-dependent mechanism. In addition, about 4.9% of leukocytes may bind endotoxin as the result of the treatment of blood smears with the preparation of glycolipid of chemotype Re. At the acute period of bacterial cerebrospinal meningitis leukocytes capable of binding endotoxin in the body or during the treatment of blood smears are practically absent. The conclusion was made that the binding of endotoxins by leukocytes had a protective character.
用与辣根过氧化物酶结合的Re化学型糖脂抗体处理薄血涂片后发现，在生理条件下，约3.5%的白细胞通过Fc依赖机制结合革兰氏阴性菌的内毒素。此外，在用Re化学型糖脂制剂处理血涂片后，约4.9%的白细胞可能会结合内毒素。在细菌性脑脊髓膜炎急性期，体内或血涂片处理过程中能够结合内毒素的白细胞实际上并不存在。得出的结论是，白细胞对内毒素的结合具有保护作用。
