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[献血者血清中的丙型肝炎病毒抗体]

[Hepatitis C virus antibody in the serum of blood donors].

作者信息

Barna T K, Ozsvár Z, Szendrényi V, Gál G

机构信息

Szent-Györgyi Albert Orvostudományi Egyetem, Szeged Vértranszfúziós Allomás.

出版信息

Orv Hetil. 1996 Mar 10;137(10):507-11.

PMID:8713664
Abstract

Authors investigated the presence of antibody to hepatitis C virus (anti-HCV) at 67,534 blood donations, and alanin-amino-transferase (ALT) levels were analysed at the same time. The prevalence of anti-HCV antibody was 0.73% at 15,864 blood donors. Frequency of positive reactions of anti-HCV antibody increased paralelly with advance of age. Increased or high serum ALT level was found at more than 50% of samples with positive HCV reactivity. At the base of follow-up the blood donors were screened out from blood donation temporarily or definitively. Anti-HCV donors were taken to hepatic care. The treatment with interferon of HCV seropositive donors proved by PCR (polimerase chain reaction) was started. Transfusion and tattou are underlined as risk factors of HCV infection. The data were analysed according to sex and ages.

摘要

作者对67534份献血样本检测了丙型肝炎病毒抗体(抗-HCV),同时分析了丙氨酸氨基转移酶(ALT)水平。在15864名献血者中,抗-HCV抗体的流行率为0.73%。抗-HCV抗体阳性反应的频率随年龄增长而平行增加。超过50%的HCV反应阳性样本血清ALT水平升高或处于高水平。在随访基础上,献血者被暂时或永久排除献血。抗-HCV献血者被送去肝脏护理。对经聚合酶链反应(PCR)证实的HCV血清阳性献血者开始进行干扰素治疗。输血和纹身被强调为HCV感染的危险因素。数据按性别和年龄进行分析。

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