Nesković N K, Poleksić V, Elezovíc I, Karan V, Budimir M
Institute for Plant Protection and Environment, Department of Toxicology, Belgrade, Yugoslavia.
Bull Environ Contam Toxicol. 1996 Feb;56(2):295-302. doi: 10.1007/s001289900044.
Glyphosate, also known by the trade names Roundup and Rodeo for agricultural use, is a broad-spectrum, translocated herbicide, used primarily in agricultural applications, and for vegetation control in non-crop areas. It is used as non-selective herbicide and for aquatic weed control in fish-ponds, lakes, canals, slow running water, etc. (USDA 1984). Glyphosate is perhaps the most important herbicide ever developed. Literature of toxicological and ecotoxicological properties of glyphosate is extremely sparse, considering its importance as herbicide. Generally, glyphosate is slightly toxic to mammals and fish, but it may have an impact on the aquatic environment and also on the other aquatic organisms (USDA 1984). Due to this, its toxicity investigation is very important. The study of sublethal effects is of special importance for toxicological evaluation of compound. The objective of this study was to investigate acute and subacute toxic effects of sublethal glyphosate concentrations in water to carp (Cyprinus carpio L.), one of the commercially most important fish species populating freshwaters of Yugoslavia.
草甘膦，在农业上也以商品名农达和罗迪欧为人所知，是一种广谱、内吸性除草剂，主要用于农业生产以及非作物区的植被控制。它用作非选择性除草剂，用于鱼塘、湖泊、运河、缓流水域等的水生杂草防治（美国农业部，1984年）。草甘膦可能是有史以来开发的最重要的除草剂。考虑到其作为除草剂的重要性，关于草甘膦毒理学和生态毒理学特性的文献极为稀少。一般来说，草甘膦对哺乳动物和鱼类有轻微毒性，但它可能会对水生环境以及其他水生生物产生影响（美国农业部，1984年）。因此，对其毒性进行研究非常重要。亚致死效应的研究对于化合物的毒理学评估尤为重要。本研究的目的是调查水中亚致死浓度的草甘膦对鲤鱼（鲤科鲤属鲤鱼）的急性和亚急性毒性效应，鲤鱼是南斯拉夫淡水水域中商业上最重要的鱼类之一。
