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在普通医疗实践中使用眼动视野计进行青光眼筛查:其特异性是否可接受?

Glaucoma screening with oculokinetic perimetry in general practice: is its specificity acceptable?

作者信息

Christoffersen T, Fors T, Waage S, Holtedahl K

机构信息

Department of Ophthalmology, University Hospital, Tromsø, Norway.

出版信息

Eye (Lond). 1995;9 ( Pt 6 Su):36-9.

PMID:8729017
Abstract

The main aim of the study was to estimate the specificity of oculokinetic perimetry (OKP) for glaucoma case-finding in general practice. The visual fields of 185 consecutive patients aged 40 years or more were screened with OKP in one general practice. Test specificity was 94%. The OKP test was abnormal in 17 patients. At follow-up 6 of these patients had glaucoma or were glaucoma suspects. Three of the remaining 11 patients had cataract. Eight OKP-positive patients had no eye disease. In 96 of the patients results of OKP were compared with Bjerrum campimetry, which revealed one possibly false-negative OKP test. Ten patients with previously diagnosed glaucoma were also examined with OKP. All 10 patients were identified by the OKP test. In 80 of the patients OKP was performed twice, supervised by two different observers. The proportion of agreement for normal tests was very high: 0.96 (95% CI: 0.91-1.0). The proportion of agreement for abnormal tests was 0.79 (95% CI: 0.57-1.0). The OKP test may be useful in glaucoma case-finding in general practice. However, the proportion of false-positive tests seems to be too high for OKP to be used alone in mass screening.

摘要

该研究的主要目的是评估在一般医疗实践中,眼球运动视野计(OKP)用于青光眼病例筛查的特异性。在一家普通诊所,对185名年龄40岁及以上的连续患者进行了OKP视野筛查。测试特异性为94%。17名患者的OKP测试结果异常。随访时,其中6名患者患有青光眼或为青光眼疑似患者。其余11名患者中有3名患有白内障。8名OKP检测呈阳性的患者没有眼部疾病。在96名患者中,将OKP结果与比耶鲁姆视野计检查结果进行了比较,发现有1例假阴性OKP检测结果。还对10名先前诊断为青光眼的患者进行了OKP检查。所有10名患者均通过OKP检测被识别出来。在80名患者中,由两名不同的观察者监督进行了两次OKP检查。正常检查结果的一致性比例非常高:0.96(95%CI:0.91 - 1.0)。异常检查结果的一致性比例为0.79(95%CI:0.57 - 1.0)。OKP检测在一般医疗实践中的青光眼病例筛查中可能有用。然而,假阳性检测的比例似乎过高,以至于OKP不能单独用于大规模筛查。

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