Meredith S, Nordman H
Department of Epidemiology and Medical Statistics, London Hospital Medical College at QMW, London, UK.
Thorax. 1996 Apr;51(4):435-40. doi: 10.1136/thx.51.4.435.
Disease registers and surveillance schemes are not necessarily designed to measure incidence and prevalence, but their data can provide useful epidemiological insights. Their main functions are the detection and identification of hazards so that further cases can be prevented, and to provide a database for research to improve our understanding of the determinants and consequences of disease. Occupational asthma probably accounts for only a small proportion of adult asthma, of the order of 2-6% in the UK. On the other hand, asthma is very common and so thousands of people in the UK and in other western countries have asthma as a result of their work. The frequency of the disease in less developed countries is unknown but is potentially very large. Information on incidence is patchy but from Finland, where ascertainment is most complete, there are approximately 140 per million working people affected each year, and even there disease in the self-employed is probably missed. Data for the UK are limited to cases seen by specialist physicians and the best estimate is that the annual incidence of such cases is about 50 per million. Through internal comparisons and analysis it is possible to judge the extent to which variation in ascertainment and reporting have affected the frequency of reported disease, but so far it has not been possible to measure the underestimation due to persons with work-related symptoms not seeking medical attention or not being referred to a specialist.
疾病登记册和监测计划并非专门用于测量发病率和患病率,但其数据能提供有用的流行病学见解。它们的主要功能是检测和识别危害因素,以便预防更多病例,并提供一个数据库用于研究,以增进我们对疾病的决定因素和后果的理解。职业性哮喘在成人哮喘中可能仅占一小部分,在英国约为2%至6%。另一方面,哮喘非常常见,因此在英国和其他西方国家,成千上万的人因工作而患哮喘。欠发达国家该病的发病频率尚不清楚,但可能非常高。关于发病率的信息并不完整,但在芬兰,确诊最为全面,每年每百万在职人员中约有140人患病,即便如此,个体经营者中的患病情况可能仍被遗漏。英国的数据仅限于专科医生诊治的病例,最佳估计是此类病例的年发病率约为每百万50例。通过内部比较和分析,可以判断确诊和报告方面的差异在多大程度上影响了报告疾病的频率,但到目前为止,尚无法衡量因有工作相关症状的人未就医或未转诊至专科医生而导致的漏报情况。