Tortori-Donati P, Fondelli M P, Rossi A, Cama A, Caputo L, Andreussi L, Garré M L
Department of Neuroradiology, Children's Hospital G. Gaslini, Genova, Italy.
Neuroradiology. 1996 May;38(4):352-9. doi: 10.1007/BF00596587.
Our purpose was to determine whether medulloblastoma (MB) shows specific neuroradiological features which may be employed in differential diagnosis from other common posterior cranial fossa tumours in childhood. Preoperative MRI was performed on 20 children with MB, and preoperative CT in 17 of them. All underwent surgery and histopathological diagnosis. There was a constant relationship between high density on CT and low signal on T1-weighted images. Signal behaviour on T2-weighted images and the degree of contrast enhancement were more variable. Most tumours arose in the midline, from the cerebellar vermis, involving the fourth ventricle, but hemisphere and extra-axial neoplasms were also seen. The combination of high density on CT and low signal on T1-weighted images is highly suggestive of MB and may assist preoperative differential diagnosis from other posterior cranial fossa tumours.
我们的目的是确定髓母细胞瘤（MB）是否具有特定的神经放射学特征，这些特征可用于与儿童期其他常见的后颅窝肿瘤进行鉴别诊断。对20例患有MB的儿童进行了术前MRI检查，其中17例进行了术前CT检查。所有患者均接受了手术及组织病理学诊断。CT上的高密度与T1加权图像上的低信号之间存在恒定关系。T2加权图像上的信号表现及对比增强程度变化更大。大多数肿瘤起源于中线，来自小脑蚓部，累及第四脑室，但也可见半球及轴外肿瘤。CT上的高密度与T1加权图像上的低信号相结合高度提示MB，可能有助于术前与其他后颅窝肿瘤进行鉴别诊断。
