Nakamura Y, Asahi S, Nakaya T, Bahmani M K, Saitoh S, Yasui K, Mayama H, Hagiwara K, Ishihara C, Ikuta K
Section of Serology, Hokkaido University, Sapporo, Japan.
J Clin Microbiol. 1996 Jan;34(1):188-91. doi: 10.1128/jcm.34.1.188-191.1996.
Borna disease virus (BDV) naturally infects horses, sheep, and several other species, including humans, and it is believed to be related to neurological disorders. BDV infection in domestic cats has also been demonstrated by serological assays. We demonstrated for the first time BDV RNA in peripheral blood mononuclear cells from 11 of 83 (13.3%) randomly selected domestic cats in Japan by nested reverse transcriptase-PCR. The BDVs from cats were similar to but slightly different from those from horses and humans, as shown by sequencing the reverse transcriptase-PCR products. None of the cats was positive for both BDV RNA and anti-BDV antibodies.
博尔纳病病毒（BDV）可自然感染马、羊以及包括人类在内的其他几种物种，并且被认为与神经紊乱有关。血清学检测也已证实家猫可感染BDV。我们通过巢式逆转录聚合酶链反应首次在日本随机选取的83只家猫中的11只（13.3%）的外周血单核细胞中检测到了BDV RNA。对逆转录聚合酶链反应产物进行测序结果显示，猫身上的BDV与马和人类身上的BDV相似但略有不同。没有一只猫的BDV RNA和抗BDV抗体均呈阳性。
