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[β受体激动剂在哮喘中的给药方式]

[Modes of administration of beta agonists in asthma].

作者信息

Salmeron S, Taravella O, Bard M, Caquet R, Duroux P

机构信息

Service de Médecine Interne, Centre Hospitalier Universitaire Bicêtre, Le Kremlin Bicêtre.

出版信息

Rev Pneumol Clin. 1996;52(2):119-27.

PMID:8761642
Abstract

Short-acting beta 2 agonists have a rapid and potent bronchodilating effect and represent the basis of treatment of acute asthma. Whatever the level of severity, the inhaled route is preferred because of its high efficacy/tolerance ratio. The doses and modes of administration depend on the severity of the airway obstruction, the site of management and the available devices. Long-acting beta 2 agonists are administered as regular treatment in moderately-severe to severe chaonic asthma in association to inhaled corticosteroids, mainly by the inhaled route whereas the oral route may be considered for the administration of prodrugs.

摘要

短效β2激动剂具有快速且强效的支气管扩张作用,是急性哮喘治疗的基础。无论严重程度如何,由于其高效/耐受性比,吸入途径是首选。剂量和给药方式取决于气道阻塞的严重程度、治疗地点和可用设备。长效β2激动剂主要通过吸入途径与吸入性糖皮质激素联合用于中度至重度慢性哮喘的常规治疗,而口服途径可考虑用于前体药物的给药。

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