泰国艾滋病流行地区献血者中丙型肝炎病毒感染的危险因素。
Risk factors for hepatitis C virus infection among blood donors in an HIV-epidemic area in Thailand.
作者信息
Sawanpanyalert P, Boonmar S, Maeda T, Matsuura Y, Miyamura T
机构信息
Department of Medical Services, Ministry of Public Health, Nonthaburi, Thailand.
出版信息
J Epidemiol Community Health. 1996 Apr;50(2):174-7. doi: 10.1136/jech.50.2.174.
OBJECTIVE
The role of sexual transmission in hepatitis C virus (HCV) infection has not yet been completely elucidated. This study aimed to compare the risk factors for HCV and human immunodeficiency virus (HIV) infection in an HIV epidemic area of Thailand where HIV is mainly transmitted heterosexually.
DESIGN AND SUBJECTS
Sera from 3053 blood donors were collected and tested for HCV and HIV between January and March 1994. Altogether 1756 (57.5%) of the donors were interviewed about demographics and several risk factors.
RESULTS
The prevalence rates of HIV and HCV infections determined by antibody assays were 2.3% and 2.2%, respectively. Sexual risk factors were clearly shown among anti-HIV positive donors. These clear associations were not found, however, among anti-HCV positive donors. In contrast, previous histories of injecting drug use and being tattooed were found in some anti-HCV positive donors but less frequently in anti-HIV positive donors.
CONCLUSIONS
Sexual transmission may play a relatively minor role in HCV transmission compared with HIV, in this area.
目的
丙型肝炎病毒（HCV）感染中性传播的作用尚未完全阐明。本研究旨在比较泰国一个主要通过异性传播HIV的HIV流行地区HCV和人类免疫缺陷病毒（HIV）感染的危险因素。
设计与研究对象
1994年1月至3月间，收集了3053名献血者的血清，并检测了HCV和HIV。共对1756名（57.5%）献血者进行了人口统计学和若干危险因素方面的访谈。
结果
通过抗体检测确定的HIV和HCV感染患病率分别为2.3%和2.2%。在抗HIV阳性献血者中，性传播危险因素明显。然而，在抗HCV阳性献血者中未发现这些明显的关联。相反，一些抗HCV阳性献血者有注射吸毒和纹身史，但在抗HIV阳性献血者中较少见。
结论
在该地区，与HIV相比，性传播在HCV传播中可能起相对较小的作用。
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