Lobetti R G
Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
J S Afr Vet Assoc. 1996 Jun;67(2):91-2.
Phaeohyphomycosis is a rare fungal disease of animals and man, generally thought to occur in compromised or debilitated hosts, although in man the majority of infections have occurred in otherwise healthy patients. To investigate the possible role of immune suppression in systemic phaeohyphomycosis, certain aspects of the immune system of 2 dogs with systemic Xylohypha bantiana infection were investigated. White cell and differential cell counts, serum protein electrophoresis and serum immunoglobulin fractions were determined. The only consistent finding was lymphopaenia. Although there is no specific evidence for it, a lymphopaenic state might predispose to systemic phaeohyphomycosis.
暗色丝孢霉病是一种罕见的人和动物真菌病,通常认为发生于免疫功能受损或身体虚弱的宿主,尽管在人类中,大多数感染发生在其他方面健康的患者身上。为了研究免疫抑制在系统性暗色丝孢霉病中的可能作用,对2只患有系统性班替木霉感染的犬的免疫系统的某些方面进行了研究。测定了白细胞和分类细胞计数、血清蛋白电泳和血清免疫球蛋白组分。唯一一致的发现是淋巴细胞减少。虽然没有具体证据,但淋巴细胞减少状态可能易患系统性暗色丝孢霉病。