采用尿硫酸化胆汁酸直接酶法检测替代血清胆红素检测用于新生儿胆汁淤积症的选择性筛查。
Direct enzymatic assay of urinary sulfated bile acids to replace serum bilirubin testing for selective screening of neonatal cholestasis.
作者信息
Matsui A, Kasano Y, Yamauchi Y, Momoya T, Shimada T, Ishikawa T, Abukawa D, Kimura A, Adachi K, Tazuke Y
机构信息
Department of Pediatrics, Jichi Medical School, Tochigi, Japan.
出版信息
J Pediatr. 1996 Aug;129(2):306-8. doi: 10.1016/s0022-3476(96)70260-3.
PMID:8765633
Abstract
Direct enzymatic assay of urinary sulfated bile acids is a sensitive, rapid, minimally invasive, and convenient method of detecting cholestasis in young infants. It may replace measurement of serum direct bilirubin for selective screening for biliary atresia and neonatal hepatitis syndrome at 1 month of age.
摘要
尿硫酸化胆汁酸的直接酶法测定是一种灵敏、快速、微创且便捷的检测婴幼儿胆汁淤积的方法。它可能替代血清直接胆红素测定，用于在1月龄时对胆道闭锁和新生儿肝炎综合征进行选择性筛查。
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