Zeller H G, Diallo M, Angel G, Traoré-Lamizana M, Thonnon J, Digoutte J P, Fontenille D
Institut Pasteur, Dakar, Sénégal.
Bull Soc Pathol Exot. 1996;89(1):12-6.
Ngari virus (NRI) (Bunyaviridae, genus Bunyavirus) was isolated first from male Aedes simpsoni mosquitoes in Southeastern Senegal in 1979. Then, it was recovered from several mosquito species in Senegal, Burkina Faso, Central African Republic and Madagascar. A potential pathogenicity of NRI virus in humans was suspected when the virus was isolated from two patients in Dakar in October and November 1993. The large diversity of Culicidae vectors and feeding patterns showed a large heterogeneity of vertebrate hosts. The wide geographical distribution of NRI virus in different bioclimatic areas indicated an important adaptability of the virus. Ngari virus epidemiology will need further investigations in order to approach the real pathogenicity of such emerging virus.
恩加里病毒(NRI)(布尼亚病毒科,布尼亚病毒属)于1979年首次从塞内加尔东南部的雄性辛普森伊蚊中分离出来。随后,在塞内加尔、布基纳法索、中非共和国和马达加斯加的几种蚊虫中也发现了该病毒。1993年10月和11月,从达喀尔的两名患者中分离出该病毒后,人们怀疑NRI病毒对人类具有潜在致病性。蚊科媒介和摄食模式的巨大多样性表明脊椎动物宿主具有很大的异质性。NRI病毒在不同生物气候区域的广泛地理分布表明该病毒具有重要的适应性。为了深入了解这种新出现病毒的实际致病性,恩加里病毒流行病学还需要进一步研究。