Croft P, Burt J, Schollum J, Thomas E, Macfarlane G, Silman A
ARC Epidemiology Research Unit, University of Manchester, United Kingdom.
Ann Rheum Dis. 1996 Jul;55(7):482-5. doi: 10.1136/ard.55.7.482.
To investigate the hypothesis that fibromyalgia represents one end of a spectrum in which there is a more general association between musculoskeletal pain and tender points.
The subjects studied were 177 individuals selected from a population based screening survey for musculoskeletal pain. All subjects completed a pain mannikin and were examined for the presence of tender points at the nine American College of Rheumatology bilateral sites.
There were moderately strong associations (odds ratios range 1.3-3.1) between the reported presence of pain in a body segment and the presence of a tender point within that segment. Further, there was evidence of a trend of increasing number of tender points with increasing number of painful segments. The reporting of non-specific pain, aching, or stiffness, was also associated with high tender point counts.
This study illustrates that the association between tender points and pain is not restricted to the clinically defined subgroup with chronic widespread pain. Given that widespread pain and tender points have previously been linked with distress, this might reflect lesser degrees, or earlier phases of the somatisation of distress.
探讨纤维肌痛代表了一个连续谱的一端这一假说,在该连续谱中,肌肉骨骼疼痛与压痛点之间存在更普遍的关联。
研究对象为从基于人群的肌肉骨骼疼痛筛查调查中选取的177名个体。所有受试者均完成了疼痛人体模型测试,并接受了美国风湿病学会指定的九个双侧部位压痛点的检查。
身体某一部位报告的疼痛与该部位存在压痛点之间存在中度强关联(优势比范围为1.3 - 3.1)。此外,有证据表明随着疼痛部位数量的增加,压痛点数量呈增加趋势。非特异性疼痛、酸痛或僵硬的报告也与高压痛点计数相关。
本研究表明,压痛点与疼痛之间的关联并不局限于临床上定义的慢性广泛性疼痛亚组。鉴于广泛性疼痛和压痛点此前已与痛苦相关联,这可能反映了痛苦躯体化的较轻程度或早期阶段。