Kamoun A, Daudon M, Kabaar N, Dhaoui R, Ben Ammar S, Zghal A, Zerilli L, Chaouachi B, Belkahia C, Lakhoua R
Service de Pédiatrie, Hôpital Charles Nicolle, Tunis, Tunisie.
Prog Urol. 1995 Dec;5(6):942-5.
Fifty-five Tunisian children with urinary stones, between the ages of 8 months and 15 years, underwent morphological and infrared spectrophotometric analysis of their stones. This study provides an approach to the aetiological profile of urinary stones in Tunisian children. The nucleus of the stones was composed of acidic ammonium urate in 48% of cases with a morphology suggestive of phosphorus deficiency associated with a history of diarrhoea. In 24% of cases, the nucleus contained struvite indicating the presence of urinary tract infection by urease-positive bacteria. The main growth factors of urinary stones were hyperoxaluria and urinary tract infection. In 5 cases, the stones were due to a hereditary lithogenic metabolic disease : cystinuria in 1 case and primary hyperoxaluria in 4 cases.
对55名年龄在8个月至15岁之间患有尿路结石的突尼斯儿童的结石进行了形态学和红外分光光度分析。本研究为突尼斯儿童尿路结石的病因学概况提供了一种研究方法。结石核心在48%的病例中由酸性尿酸铵组成，其形态提示与腹泻病史相关的磷缺乏。在24%的病例中，结石核心含有鸟粪石，表明存在脲酶阳性细菌引起的尿路感染。尿路结石的主要生长因素是高草酸尿症和尿路感染。在5例中，结石是由遗传性致石代谢疾病引起的：1例为胱氨酸尿症，4例为原发性高草酸尿症。
