Ohuchi H, Nakajima T, Kawade M, Matsuda M, Kamiya T
Department of Pediatrics, National Cardiovascular Center, Osaka, Japan.
Pediatr Cardiol. 1996 Jan-Feb;17(1):7-14. doi: 10.1007/BF02505805.
The purpose of the present study was to measure oxygen uptake (VO2) at the ventilatory threshold (VT) in patients with congenital heart disease using a progressive exercise protocol on a treadmill and to evaluate the validity and feasibility of this procedure. Eight control subjects and seventeen patients performed a maximal exercise test with breath-by-breath measurement of ventilation and gas exchange variables. VT(VE) was determined by the change in the ventilatory equivalent for VO2 and carbon dioxide output, VT(V-sl) by the V-slope method, and the lactate threshold (LT) by the change in blood lactate concentration; these parameters were determined in 100%, 88%, and 96% of subjects, respectively. The interobserver error among three evaluators was not significant, and LT was correlated with each VT (r = 0.97, 0.92; p = 0.0001) and with peak VO2 (r = 0.91; p = 0.0001). The VTs were correlated with each other when expressed as milliliter per minute and milliliters per kilogram per minute. It was concluded that a progressive exercise protocol on a treadmill was a feasible procedure for determining the VTs in most individuals and that VTs were valid, useful parameters for evaluating submaximal exercise tolerance in patients with congenital heart disease.
本研究的目的是使用跑步机上的渐进性运动方案，测量先天性心脏病患者在通气阈值（VT）时的摄氧量（VO2），并评估该程序的有效性和可行性。8名对照受试者和17名患者进行了最大运动测试，逐次呼吸测量通气和气体交换变量。通过VO2通气当量和二氧化碳排出量的变化确定VT(VE)，通过V斜率法确定VT(V-sl)，通过血乳酸浓度变化确定乳酸阈值（LT）；这些参数分别在100%、88%和96%的受试者中确定。三名评估者之间的观察者间误差不显著，LT与每个VT相关（r = 0.97, 0.92；p = 0.0001），并与峰值VO2相关（r = 0.91；p = 0.0001）。当以每分钟毫升数和每千克每分钟毫升数表示时，VTs相互相关。得出的结论是，跑步机上的渐进性运动方案是确定大多数个体VTs的可行程序，并且VTs是评估先天性心脏病患者次最大运动耐力的有效、有用参数。
