Could coenzyme Q10 and L-carnitine be a treatment for diabetes secondary to 3243 mutation of mtDNA?

Suppr

超能文献

作者信息

Silvestre-Aillaud P, BenDahan D, Paquis-Fluckinger V, Pouget J, Pelissier J F, Desnuelle C, Cozzone P J, Vialettes B

出版信息

Diabetologia. 1995 Dec;38(12):1485-6. doi: 10.1007/BF00400614.

DOI:10.1007/BF00400614

PMID:8786027

Abstract

摘要

相似文献

Could coenzyme Q10 and L-carnitine be a treatment for diabetes secondary to 3243 mutation of mtDNA?

Diabetologia. 1995 Dec;38(12):1485-6. doi: 10.1007/BF00400614.

Diabetes mellitus associated with 3243 mitochondrial tRNA(Leu(UUR)) mutation: clinical features and coenzyme Q10 treatment.

Mol Aspects Med. 1997;18 Suppl:S181-8. doi: 10.1016/s0098-2997(97)00041-1.

The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation.辅酶Q10治疗对母系遗传糖尿病伴耳聋及线粒体DNA 3243（A到G）突变的影响。

Diabetologia. 1998 May;41(5):584-8. doi: 10.1007/s001250050950.

Insulin sensitivity in patients with NIDDM and the A-to-G mutation at nucleotide 3,243 of the mitochondrial tRNALeu(UUR) gene.

Diabetes Care. 1995 Jun;18(6):886-8. doi: 10.2337/diacare.18.6.886b.

[Patient with diabetes and impaired hearing].患有糖尿病且听力受损的患者。

Endocrinol Nutr. 2012 Mar;59(3):220-2. doi: 10.1016/j.endonu.2011.08.006. Epub 2011 Dec 5.

Beta-cell function in individuals carrying the mitochondrial tRNA leu (UUR) mutation.携带线粒体tRNA亮氨酸（UUR）突变个体的β细胞功能。

Pancreas. 2007 Jan;34(1):133-7. doi: 10.1097/01.mpa.0000246659.38375.4d.

Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation.线粒体tRNALeu(UUR)基因突变所致母系遗传糖尿病伴耳聋家系的临床表型、胰岛素分泌及胰岛素敏感性

Diabetes. 1996 Apr;45(4):478-87. doi: 10.2337/diab.45.4.478.

Beware the thin, deaf 'type 2' diabetic: maternally inherited diabetes and deafness with systemic (mitochondrial) manifestations.警惕体型消瘦、耳聋的“2型”糖尿病患者：母系遗传的糖尿病伴耳聋及全身（线粒体）表现。

Intern Med J. 2004 Aug;34(8):517-8. doi: 10.1111/j.1444-0903.2004.00659.x.

Myocardial dysfunction in mitochondrial diabetes treated with Coenzyme Q10.辅酶Q10治疗线粒体糖尿病中的心肌功能障碍。

Diabetes Res Clin Pract. 2006 Apr;72(1):100-3. doi: 10.1016/j.diabres.2005.09.005. Epub 2005 Oct 25.

Diminished insulin secretory response to glucose but normal insulin and glucagon secretory responses to arginine in a family with maternally inherited diabetes and deafness caused by mitochondrial tRNA(LEU(UUR)) gene mutation.在一个因线粒体tRNA（亮氨酸（UUR））基因突变导致母系遗传糖尿病和耳聋的家族中，胰岛素对葡萄糖的分泌反应减弱，但胰岛素和胰高血糖素对精氨酸的分泌反应正常。

Diabetes Care. 2001 Jul;24(7):1253-8. doi: 10.2337/diacare.24.7.1253.

引用本文的文献

Low prevalence of patients with mitochondrial disease in the German/Austrian DPV diabetes registry.德国/奥地利糖尿病患者虚拟队列登记中，线粒体疾病患者的低患病率。

Eur J Pediatr. 2016 May;175(5):613-22. doi: 10.1007/s00431-015-2675-5. Epub 2015 Dec 15.

本文引用的文献

Adult-onset diabetes mellitus and neurosensory hearing loss in maternal relatives of MELAS patients in a family with the tRNA(Leu(UUR)) mutation.携带tRNA（Leu（UUR））突变的家族中，MELAS患者母系亲属的成人发病型糖尿病和神经感觉性听力损失。

Neurology. 1993 May;43(5):1015-20. doi: 10.1212/wnl.43.5.1015.

Diabetes mellitus is one of the heterogeneous phenotypic features of a mitochondrial DNA point mutation within the tRNALeu(UUR) gene.糖尿病是tRNALeu（UUR）基因中线粒体DNA点突变的异质表型特征之一。

FEBS Lett. 1993 Apr 26;321(2-3):194-6. doi: 10.1016/0014-5793(93)80106-5.

A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA.一种与线粒体DNA突变相关的糖尿病亚型。

N Engl J Med. 1994 Apr 7;330(14):962-8. doi: 10.1056/NEJM199404073301403.

Mitochondrial gene mutation in islet-cell-antibody-positive patients who were initially non-insulin-dependent diabetics.最初为非胰岛素依赖型糖尿病的胰岛细胞抗体阳性患者的线粒体基因突变。

Lancet. 1993 Aug 28;342(8870):527-8. doi: 10.1016/0140-6736(93)91649-7.

Mitochondrial gene defects in patients with NIDDM.非胰岛素依赖型糖尿病患者的线粒体基因缺陷

Diabetologia. 1994 Apr;37(4):372-6. doi: 10.1007/BF00408473.

Mitochondrial diabetes mellitus: prevalence and clinical characterization of diabetes due to mitochondrial tRNA(Leu(UUR)) gene mutation in Japanese patients.线粒体糖尿病：日本患者中线粒体tRNA（Leu（UUR））基因突变所致糖尿病的患病率及临床特征

Diabetologia. 1994 May;37(5):504-10. doi: 10.1007/s001250050139.

Diabetes mellitus carrying a mutation in the mitochondrial tRNA(Leu(UUR)) gene.携带线粒体tRNA（Leu（UUR））基因突变的糖尿病。

Diabetologia. 1995 Feb;38(2):193-200. doi: 10.1007/BF00400094.

Mitochondrial encephalomyopathy (MELAS): pathological study and successful therapy with coenzyme Q10 and idebenone.线粒体脑肌病（MELAS）：病理研究及辅酶Q10和艾地苯醌的成功治疗

J Neurol Sci. 1989 May;90(3):263-71. doi: 10.1016/0022-510x(89)90112-3.

Long-term coenzyme Q10 therapy for a mitochondrial encephalomyopathy with cytochrome c oxidase deficiency: a 31P NMR study.辅酶Q10长期治疗细胞色素c氧化酶缺乏的线粒体脑肌病：一项31P核磁共振研究

Neurology. 1989 Mar;39(3):399-403. doi: 10.1212/wnl.39.3.399.

Heterogeneity of metabolic response to muscular exercise in humans. New criteria of invariance defined by in vivo phosphorus-31 NMR spectroscopy.人类肌肉运动代谢反应的异质性。由体内磷-31核磁共振波谱定义的不变性新标准。

FEBS Lett. 1990 Oct 15;272(1-2):155-8. doi: 10.1016/0014-5793(90)80472-u.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验