Alb J G, Kearns M A, Bankaitis V A
Department of Cell Biology, University of Alabama at Birmingham, 35294-0005, USA.
Curr Opin Cell Biol. 1996 Aug;8(4):534-41. doi: 10.1016/s0955-0674(96)80032-9.
Genetic and biochemical approaches are shedding new light on the distinct physiological functions of specific phospholipid metabolic pathways and the mechanisms by which phospholipids are mobilized between intracellular compartments. In particular, phosphatidylinositol-transfer proteins have recently been revealed to play fascinating and unanticipated roles in the coordination of phospholipid metabolism with vesicle-trafficking and signal-transducing reactions.
遗传和生物化学方法正在为特定磷脂代谢途径的独特生理功能以及磷脂在细胞内区室之间转运的机制带来新的认识。特别是，最近发现磷脂酰肌醇转移蛋白在磷脂代谢与囊泡运输和信号转导反应的协调中发挥着迷人且意想不到的作用。
