Denton M, Todd N J, Littlewood J M
Department of Microbiology, St. James's University Hospital, Leeds, UK.
Eur J Clin Microbiol Infect Dis. 1996 May;15(5):402-5. doi: 10.1007/BF01690098.
A retrospective case-control study of 12 patients positive for Stenotrophomonas maltophilia and 24 age-sex-matched controls revealed that in the year prior to initial isolation, colonised patients spent more days in hospital and received more days of oral ciprofloxacin, intravenous anti-pseudomonal antibiotics, and nebulised aminoglycosides. They were also more likely to have grown Pseudomonas aeruginosa at some time in the past, despite there being no difference in current chronic infection with this organism. The role of anti-pseudomonal antibiotics in promoting Stenotrophomonas maltophilia colonisation in cystic fibrosis is discussed.
一项针对12例嗜麦芽窄食单胞菌阳性患者及24例年龄和性别匹配的对照者的回顾性病例对照研究显示，在首次分离前的一年中，定植患者的住院天数更多，接受口服环丙沙星、静脉注射抗假单胞菌抗生素和雾化氨基糖苷类药物的天数也更多。尽管目前该菌的慢性感染情况并无差异，但他们过去曾有过铜绿假单胞菌生长的可能性也更高。本文讨论了抗假单胞菌抗生素在促进囊性纤维化患者嗜麦芽窄食单胞菌定植中的作用。
