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共面和非共面多氯联苯对灰海豹(Halichoerus grypus)乳汁毒性当量的贡献。

Contribution of coplanar and non-coplanar polychlorinated biphenyls to the toxic equivalence of grey seal (Halichoerus grypus) milk.

作者信息

Green N J, Jones K C, Harwood J

机构信息

Institute of Environmental and Biological Sciences, Lancaster University, UK.

出版信息

Chemosphere. 1996 Oct;33(7):1273-81. doi: 10.1016/0045-6535(96)00265-2.

DOI:10.1016/0045-6535(96)00265-2
PMID:8799994
Abstract

We measured the concentration of coplanar polychlorinated biphenyl (PCB) congeners #77, #126 and #169 in the milk of 21 individual grey seals (Halichoerus grypus) from the same Scottish colony. Using the toxic equivalency factors (TEFs) of Ahlborg et al. (1994) we found TEQs ranged between 8.4 and 45.7 pg/g, with a mean of 22.3 +/- 9.3 pg/g on a lipid weight basis (n = 32). For some samples we also had concentrations of mono-ortho and di-orthochlorinated PCBs. Inclusion of these congeners approximately doubled the TEQ. There was a good correlation between the concentration of non-ortho PCBs and that of other congeners in the same sample.

摘要

我们测量了来自同一苏格兰海豹栖息地的21只灰海豹(Halichoerus grypus)乳汁中共平面多氯联苯(PCB)同系物#77、#126和#169的浓度。利用阿尔伯格等人(1994年)的毒性当量因子(TEF),我们发现毒性当量(TEQ)在8.4至45.7皮克/克之间,以脂质重量计,平均值为22.3±9.3皮克/克(n = 32)。对于一些样本,我们还检测了单邻位和双邻位氯化多氯联苯的浓度。将这些同系物纳入计算后,TEQ大约增加了一倍。同一样本中,非邻位多氯联苯的浓度与其他同系物的浓度之间存在良好的相关性。

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