Chiodini P L, Conlon C P, Hutchinson D B, Farquhar J A, Hall A P, Peto T E, Birley H, Warrell D A
Department of Clinical Parasitology, Hospital for Tropical Diseases, London.
J Antimicrob Chemother. 1995 Dec;36(6):1073-8. doi: 10.1093/jac/36.6.1073.
The activity of atovaquone in patients with oligosymptomatic Plasmodium falciparum malaria was assessed in an open, non-comparative clinical study. The patients showed a good clinical response, but there was a high rate of recrudescence. The activity of atovaquone in combination with another antimalarial agent should be investigated.
在一项开放性、非对照临床研究中评估了阿托伐醌对症状轻微的恶性疟原虫疟疾患者的疗效。患者显示出良好的临床反应，但复发率很高。应研究阿托伐醌与另一种抗疟药联合使用的疗效。
