Malo J L, Pepys J, Simon G
Thorax. 1977 Jun;32(3):262-8. doi: 10.1136/thx.32.3.262.
The characteristics and the incidence of changes in plain chest radiographs were analysed in detail in 50 asthmatic patients with chronic allergic bronchopulmonary aspergillosis in whom the diagnosis had been made from 2 to 25 years previously (mean duration 10-9 years). One thousand two hundred and forty-two chest radiographs, an average of about two per year per patient, were reviewed. Two hundred and sixty-seven acute episodes of transient shadows (a mean of 5-3 per patient), mostly homogeneous consolidations and band-like shadows, were recorded throughout the period of follow-up. Features of overinflation were present in 21 patients in the first radiograph and in 17 in the last, the decrease being attributed to the effects of permanent lung damage due to the allergic aspergillosis. Permanent changes, such as tubular and ring shadows, loss of vascular shadows, and lobar shrinkage were recorded in 41 patients at the start and in 49 at the end of the follow-up. The tubular shadows were found in 28 patients in the first radiograph and in 45 in the last, whereas ring shadows were seen in 18 and 30 patients respectively. Half of the episodes of consolidation and atelectasis left permanent changes, mainly ring shadows, as seen in the last radiograph. Of the band-like shadows, 32% were found to be followed by the subsequent appearance of tubular shadows. Statistically significant correlations were found between the duration of aspergillosis, the number of transient shadows throughout the period of follow-up, the extent of the permanent shadows, and the reduction of gas transfer factor at the time of the final follow-up.
对50例慢性变应性支气管肺曲霉菌病哮喘患者的胸部X线平片变化特征及发生率进行了详细分析,这些患者的诊断时间为2至25年前(平均病程10.9年)。共回顾了1242张胸部X线片,平均每位患者每年约2张。在整个随访期间,记录到267次短暂阴影的急性发作(平均每位患者5.3次),主要为均匀性实变和带状阴影。21例患者的首张X线片出现过度充气特征,17例患者的最后一张X线片出现过度充气特征,这种减少归因于变应性曲霉菌病导致的永久性肺损伤的影响。随访开始时,41例患者记录到永久性改变,如管状和环状阴影、血管阴影消失及肺叶萎缩,随访结束时为49例。首张X线片有28例患者出现管状阴影,最后一张X线片有45例;环状阴影分别见于18例和30例患者。一半的实变和肺不张发作留下了永久性改变,主要是最后一张X线片中所见的环状阴影。在带状阴影中,32%随后出现了管状阴影。在曲霉菌病病程、整个随访期间短暂阴影的数量、永久性阴影的范围以及最后一次随访时气体交换因子的降低之间发现了具有统计学意义的相关性。