Ritchie J K, Lennard-Jones J E
Scand J Gastroenterol. 1976;11(5):433-6.
This study describes the clinical features and management of 80 patients with Crohn's disease affecting initially only the rectum with or without involvement of the sigmoid colon. Most patients were treated medically, and the various measures used are considered; the cumulative probability of completing five years under conservative management was 60% among survivors. The related mortality was very low and confined to patients treated surgically; with 655.24 patient-years of follow-up the number of observed deaths was lower than the number expected from all causes. Since this distribution of the disease is usually seen in older patients and carries a favourable prognosis, it it suggested that it should be considered as a well-defined variant of the condition.
本研究描述了80例最初仅累及直肠、伴或不伴有乙状结肠受累的克罗恩病患者的临床特征及治疗情况。大多数患者接受了药物治疗，并对所采用的各种措施进行了考量；在存活患者中，保守治疗下完成五年治疗的累积概率为60%。相关死亡率很低，且仅限于接受手术治疗的患者；在655.24患者年的随访中，观察到的死亡人数低于所有原因预期的死亡人数。由于这种疾病分布通常见于老年患者且预后良好，因此建议将其视为该疾病的一种明确变体。
