Genovese A, Spadaro G, Santoro L, Gasparo Rippa P, Onorati A M, Marone G
Division of Clinical Immunology and Allergy, University of Naples Federico II, Italy.
Int J Clin Lab Res. 1996;26(2):132-5. doi: 10.1007/BF02592356.
Hypokalemic myopathy may occur in several infections. We report a case of severe and transient myopathy secondary to hypokalemia induced by chronic intestinal infection with Giardia lamblia in a patient with common variable hypogammaglobulinemia. Hypokalemic myopathy is documented by serum enzymes, electromyography (reduction in the number of voluntarily activated motor unit action potentials and an increase in polyphasic motor unit action potentials, and pathological changes (hematoxylin-eosin, ATPase staining). The case reported involves hypokalemic myopathy induced by giardiasis in a patient with primary immunodeficiency; the histopathological changes observed in a skin/muscle biopsy from this patient are described for the first time.
低钾性肌病可能发生于多种感染中。我们报告了一例严重且短暂的肌病病例，该病例继发于一名普通可变型低丙种球蛋白血症患者因感染蓝氏贾第鞭毛虫导致的慢性肠道感染所引起的低钾血症。血清酶、肌电图（自主激活运动单位动作电位数量减少及多相运动单位动作电位增加）以及病理变化（苏木精-伊红染色、ATP酶染色）证实了低钾性肌病。所报告的病例涉及一名原发性免疫缺陷患者因贾第虫病诱发的低钾性肌病；首次描述了该患者皮肤/肌肉活检中观察到的组织病理学变化。
