一名人类免疫缺陷病毒患者发生的水痘-带状疱疹病毒性球后视神经炎。
Varicella-zoster virus retrobulbar optic neuritis in a patient with human immunodeficiency virus.
作者信息
Shayegani A, Odel J G, Kazim M, Hall L S, Bamford N, Schubert H
机构信息
Department of Ophthalmology, Edward S. Harkness Eye Institute, USA.
出版信息
Am J Ophthalmol. 1996 Oct;122(4):586-8. doi: 10.1016/s0002-9394(14)72127-0.
PURPOSE
To determine the cause of bilateral retrobulbar optic neuritis followed by progressive outer retinal necrosis in a patient with human immunodeficiency virus (HIV).
METHODS
Extensive ophthalmologic, neurologic, infectious disease, rheumatologic, and radiologic examinations were performed.
RESULTS
Cerebrospinal fluid samples taken after the onset of bilateral retrobulbar optic neuritis and before the development of clinical progressive outer retinal necrosis disclosed varicella-zoster virus from polymerase chain reaction and viral culture.
CONCLUSION
Ophthalmologists and neurologists should consider varicella-zoster virus optic neuritis as a potential precursor of progressive outer retinal necrosis and as a cause of retrobulbar optic neuritis in patients infected with HIV.
目的
确定一名人类免疫缺陷病毒（HIV）感染者出现双侧球后视神经炎并继发进行性外层视网膜坏死的病因。
方法
进行了全面的眼科、神经科、传染病科、风湿科及放射学检查。
结果
在双侧球后视神经炎发作后且临床进行性外层视网膜坏死出现之前采集的脑脊液样本，经聚合酶链反应和病毒培养检测出水痘-带状疱疹病毒。
结论
眼科医生和神经科医生应将水痘-带状疱疹病毒性视神经炎视为HIV感染患者进行性外层视网膜坏死的潜在前驱病变以及球后视神经炎的病因。
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