Rho家族小GTP酶：细胞骨架及其他
Rho family GTPases: the cytoskeleton and beyond.
作者信息
Symons M
机构信息
Onyx Pharmaceuticals, Richmond, CA 94806, USA.
出版信息
Trends Biochem Sci. 1996 May;21(5):178-81.
PMID:8871402
Abstract
Until recently, members of the Rho family of GTPases were considered primarily to be regulators of the distinct structures making up the actin cytoskeleton. Several Rho GTPases have now also been shown to play an important role in cell transformation. In addition, Cdc42, Rac and Rho activate transcription, providing a possible mechanism for their role in growth control.
摘要
直到最近，GTP酶Rho家族的成员主要被认为是构成肌动蛋白细胞骨架的不同结构的调节因子。现在已经证明，几种Rho GTP酶在细胞转化中也起着重要作用。此外，Cdc42、Rac和Rho激活转录，为它们在生长控制中的作用提供了一种可能的机制。
Zotero 插件