Parle-McDermott A G, Hand N J, Goulding S E, Wolfe K H
Department of Genetics, University of Dublin, Trinity College, Ireland.
Yeast. 1996 Sep;12(10B Suppl):999-1004. doi: 10.1002/(SICI)1097-0061(199609)12:10B%3C999::AID-YEA976%3E3.0.CO;2-E.
We report a 29,445 bp sequence from the right arm of yeast chromosome XV. It contains the genes MYO2, SNC2, PDR10, SCD5 (also called FTB1), MIP1, VMA4, MRS2, ALA1, KRE5, TEA1, and a homologue of YAL034c. Several discrepancies with previously published sequences were found. PDR10 encodes a protein highly similar to the pleiotropic drug resistance protein Pdr5p. This sequence contig forms part of a region of extended similarity to part of the left arm of chromosome I, which is a relic of an ancient duplicated chromosomal region.
我们报道了酵母第十五号染色体右臂上一段29445 bp的序列。它包含MYO2、SNC2、PDR10、SCD5(也称为FTB1)、MIP1、VMA4、MRS2、ALA1、KRE5、TEA1基因,以及YAL034c的一个同源物。发现了与先前发表序列的几处差异。PDR10编码一种与多药耐药蛋白Pdr5p高度相似的蛋白质。这个序列重叠群构成了与第一条染色体左臂部分区域存在广泛相似性的区域的一部分,该区域是一个古老的重复染色体区域的遗迹。