一种从化脓性链球菌上清液中纯化化脓性链球菌热原性外毒素A的新方法。
A new procedure for the purification of streptococcal pyrogenic exotoxin A from Streptococcus pyogenes supernatant.
作者信息
Mascini E M, Hazenberg M A, Verhage L A, Holm S E, Verhoef J, van Dijk H
机构信息
Eijkman-Winkler Institute for Microbiology, Utrecht University Hospital, The Netherlands.
出版信息
Clin Diagn Lab Immunol. 1996 Nov;3(6):779-81. doi: 10.1128/cdli.3.6.779-781.1996.
Abstract
An important role in the pathogenesis of invasive group A streptococcal disease has been ascribed to the production of streptococcal pyrogenic exotoxin A. We present a new technique for the purification of streptococcal pyrogenic exotoxin A from Streptococcus pyogenes NY-5 supernate, which is highly efficient with respect to yield (35%), purity (> or = 99%), and time.
摘要
A群链球菌侵袭性疾病发病机制中一个重要作用已归因于化脓性链球菌致热外毒素A的产生。我们提出了一种从化脓性链球菌NY - 5培养上清液中纯化化脓性链球菌致热外毒素A的新技术，该技术在产量（35%）、纯度（≥99%）和时间方面效率很高。
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