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丙二醇和乙醇对离体血管中3H-去甲肾上腺素流出的影响。

Effect of propylene glycol and ethanol on 3H-noradrenaline efflux from an isolated blood vessel.

作者信息

Schrold J, Nedergaard O A

出版信息

Experientia. 1977 Sep 15;33(9):1208-10. doi: 10.1007/BF01922333.

DOI:10.1007/BF01922333
PMID:891881
Abstract

Propylene glycol (14 mM), but not ethanol (17 mM), enhanced the late phase of passive 3H-efflux from rabbit isolated aortic rings preloaded with 3H-(-)-noradrenaline. We conclude that, with regard to 3H-noradrenaline release studies, propylene glycol is unsuitable for aiding the dissolution of e.g. corticosterone in physiological salt solution, while ethanol can be used for this purpose.

摘要

丙二醇（14毫摩尔），而非乙醇（17毫摩尔），增强了预先用3H-（-）-去甲肾上腺素负载的兔离体主动脉环被动3H外流的后期阶段。我们得出结论，就3H-去甲肾上腺素释放研究而言，丙二醇不适用于辅助例如皮质酮在生理盐溶液中的溶解，而乙醇可用于此目的。

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Effect of propylene glycol and ethanol on 3H-noradrenaline efflux from an isolated blood vessel.丙二醇和乙醇对离体血管中3H-去甲肾上腺素流出的影响。
Experientia. 1977 Sep 15;33(9):1208-10. doi: 10.1007/BF01922333.
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[The effects of etomidate on myocardial relaxation in the rat depend on the solvent, propylene glycol or ethanol].
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[Inhibition of neutrophil function by solvent of injectable sedatives--effects of propylene glycol, ethanol and benzyl alcohol].
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引用本文的文献

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本文引用的文献

1
Inhibition of catecholamine Uptake-2 by steroids in the isolated rat heart.甾体类物质对离体大鼠心脏中儿茶酚胺摄取-2的抑制作用。
Br J Pharmacol. 1970 Nov;40(3):528-30. doi: 10.1111/j.1476-5381.1970.tb10637.x.
2
Release 3H-noradrenaline from incubated and superfused rabbit pulmonary artery.从孵育并经超灌注处理的兔肺动脉中释放3H-去甲肾上腺素。
Acta Physiol Scand. 1973 Nov;89(3):296-305. doi: 10.1111/j.1748-1716.1973.tb05524.x.
3
Evaluation of mechanisms controlling the release and inactivation of the adrenergic transmitter in the rabbit portal vein and vas deferens.
家兔门静脉和输精管中肾上腺素能递质释放及失活调控机制的评估
Br J Pharmacol. 1972 Mar;44(3):472-91. doi: 10.1111/j.1476-5381.1972.tb07285.x.
4
The release of H3-norepinephrine in arterial strips studied by the technique of superfusion and transmural stimulation.通过灌流和跨壁刺激技术研究动脉条中H3-去甲肾上腺素的释放。
J Pharmacol Exp Ther. 1970 Mar;172(1):62-8.
5
Effects of ethanol on norepinephrine uptake and electrically stimulated release in brain tissue.乙醇对脑组织中去甲肾上腺素摄取及电刺激释放的影响。
Ann N Y Acad Sci. 1973 Apr 30;215:38-48. doi: 10.1111/j.1749-6632.1973.tb28246.x.
6
Comparison of the effects of clonidine on pre- and postsynaptic adrenoceptors in the rabbit pulmonary artery. Alpha-sympathomimetic inhibition of Neurogenic vasoconstriction.可乐定对兔肺动脉突触前和突触后肾上腺素能受体作用的比较。神经源性血管收缩的α-拟交感神经抑制作用。
Naunyn Schmiedebergs Arch Pharmacol. 1974;285(2):133-50. doi: 10.1007/BF00501149.
7
Factors determining the rate of relaxation of rabbit aortic strips after an exposure to noradrenaline.暴露于去甲肾上腺素后决定兔主动脉条舒张速率的因素。
Naunyn Schmiedebergs Arch Pharmacol. 1976 Jun;293(3):235-44. doi: 10.1007/BF00507346.
8
Inhibition by ethanol of noradrenaline output from peripheral sympathetic nerves: possible interaction of ethanol with neuronal receptors.乙醇对外周交感神经去甲肾上腺素释放的抑制作用：乙醇与神经元受体的可能相互作用。
Eur J Pharmacol. 1976 Jun;37(2):321-8. doi: 10.1016/0014-2999(76)90040-6.
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The effect of cocaine on the distribution of labelled noradrenaline in rabbit aortic strips and on efflux of radioactivity from the strips.可卡因对家兔主动脉条中标记去甲肾上腺素分布及条带放射性流出的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1976;292(3):231-41. doi: 10.1007/BF00517383.
10
The distribution of 3H-(+/-)noradrenaline in rabbit aortic strips after inhibition of the noradrenaline-metabolizing enzymes.去甲肾上腺素代谢酶抑制后兔主动脉条中3H-(+/-)去甲肾上腺素的分布
Naunyn Schmiedebergs Arch Pharmacol. 1976;292(3):205-17. doi: 10.1007/BF00517381.