Ljungqvist A, Unge G
J Appl Physiol Respir Environ Exerc Physiol. 1977 Aug;43(2):306-7. doi: 10.1152/jappl.1977.43.2.306.
The capillary proliferative activity in heart and skeletal muscle was studied by autoradiography after in vivo injections of [3H]thymidine in swimming exercised rats. Swimming exercise led to hypertrophy of the myocardium and the muscle fibers of the fore- and hindlimbs. When compared with normal controls a highly significant increase in nuclear incorporation of [3H]thymidine was found in the cells of the myocardial capillary walls. No increased incorporation of [3H]thymidine was found in capillary wall cells of fore- and hindlimb muscles. The findings confirm previous observations of a significant neoformation of myocardial capillary blood vessels in swimming-induced cardiac hypertrophy, whereas any capillary neoformation in the hypertrophying skeletal muscles of this experimental model is insignificant.
通过对游泳训练的大鼠进行体内注射[3H]胸腺嘧啶核苷后，利用放射自显影术研究了心脏和骨骼肌中的毛细血管增殖活性。游泳训练导致心肌以及前肢和后肢的肌纤维肥大。与正常对照组相比，发现心肌毛细血管壁细胞中[3H]胸腺嘧啶核苷的核掺入量显著增加。在前肢和后肢肌肉的毛细血管壁细胞中未发现[3H]胸腺嘧啶核苷掺入增加。这些发现证实了先前的观察结果，即在游泳诱导的心脏肥大中，心肌毛细血管有显著的新生，而在该实验模型的肥大骨骼肌中，任何毛细血管新生都不明显。
