Bar-Or O, Neuman I, Dotan R
J Allergy Clin Immunol. 1977 Sep;60(3):163-8. doi: 10.1016/0091-6749(77)90119-1.
Among factors which possibly influence the responses of asthmatic children to exercise, climate has received little attention. This study was performed to determine whether the level of air humidity is a factor to be considered. Twenty asthmatic (extrinsic perennial) girls and boys, 6 to 14 yr of age, with unverified history of exercise-induced asthma (EIA) took part. They rested and exercised in a climatic chamber in dry (25% relative humidity) and humid (90%) sessions at 25 degrees to 26 degrees C. One to three weeks separated the sessions, the order of which was counterbalanced. No changes in pulmonary functions (FVC, FEV 1.0, MMEF, MBC) were found following a sitting period of 60 min in either climate. Five and ten minutes following the treadmill run, however, bronchoconstriction was distinctly more pronounced in the dry than in the humid climate. Exercise heart rate and the subjective rating of effort were not affected by climate. It was concluded that, under the above experimental conditions, EIA is more likely in dry air than in humid air, possibly due to heat loss at the airway mucosa caused by evaporation. High humidity of inspired air could be the reason why EIA is less prevalent in swimming, as compared with other modes of exercise.
在可能影响哮喘儿童运动反应的因素中,气候很少受到关注。本研究旨在确定空气湿度水平是否是一个需要考虑的因素。20名6至14岁的哮喘(外源性常年性)女孩和男孩参与其中,他们有未经证实的运动诱发性哮喘(EIA)病史。他们在气候舱中于25%相对湿度(干燥)和90%相对湿度(潮湿)条件下,在25至26摄氏度环境中休息和运动。两次测试之间间隔一至三周,测试顺序相互抵消。在两种气候条件下静坐60分钟后,肺功能(FVC、FEV 1.0、MMEF、MBC)均未发现变化。然而,在跑步机跑步后5分钟和10分钟时,干燥气候下的支气管收缩明显比潮湿气候下更显著。运动心率和主观用力评分不受气候影响。得出的结论是,在上述实验条件下,与潮湿空气相比,干燥空气中发生运动诱发性哮喘的可能性更大,这可能是由于气道黏膜蒸发导致热量损失所致。与其他运动方式相比,吸入空气的高湿度可能是游泳中运动诱发性哮喘不太常见的原因。