Meltzer M I
Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Emerg Infect Dis. 1996 Oct-Dec;2(4):343-9. doi: 10.3201/eid0204.960411.
Any cost-benefit analysis of the use of an oral vaccine to control raccoon rabies should include calculating both costs and benefits in terms of $/unit area. Further, cost savings must be adjusted to match the stages of an epizootic: pre-epizootic, epizootic, and post-epizootic. A generic model, which can be adapted to different sites, illustrates the use of threshold analysis to link distribution costs, cost savings, bait density, and vaccine price. Initial results indicate the need to lower the cost of the vaccine, continue research to determine optimal bait densities, and examine distribution plans that do not require continued protection of areas in which raccoon rabies was eliminated through previous vaccination programs.
任何关于使用口服疫苗控制浣熊狂犬病的成本效益分析都应包括按每单位面积计算成本和效益。此外，成本节约必须根据动物疫病流行的不同阶段进行调整：流行前、流行期和流行后。一个可适用于不同地点的通用模型说明了如何使用阈值分析来关联分发成本、成本节约、诱饵密度和疫苗价格。初步结果表明，有必要降低疫苗成本，继续开展研究以确定最佳诱饵密度，并研究那些不需要持续保护通过先前疫苗接种计划已消除浣熊狂犬病的地区的分发计划。
