National Wildlife Research Center, 4101 LaPorte Ave., Fort Collins, CO 80521, USA.
Transbound Emerg Dis. 2013 Aug;60(4):330-7. doi: 10.1111/j.1865-1682.2012.01351.x. Epub 2012 Jun 19.
Beginning in 2006, point infection control operations and aerial distribution of oral rabies vaccines along the US border were performed in Quebec, Canada, to control the potential spread of raccoon rabies. A benefit-cost analysis assessed the economic efficiency of this rabies control programme into the future. In this study, a mathematical simulation model was used to determine the potential spread of raccoon rabies from the 2006 index case, and incidence rates of human post-exposure prophylaxis (PEP), animal testing and human exposure investigations were calculated. Benefits were calculated as the potential savings from reduced numbers of human PEP, animal testing and human exposure investigations owing to control, which ranged from $47 million to $53 million. Programme cost scenarios were based on projections of total expenditures, which ranged from $33 million to $49 million. Economic efficiency was indicated for approximately half of the modelled scenarios, with the greatest benefit-cost ratios resulting from reduced future programme costs.
自 2006 年起，在加拿大魁北克省开展了针对美国边境地区的定点感染控制行动和空中投放口服狂犬病疫苗，以控制浣熊狂犬病的潜在传播。一项效益成本分析评估了该狂犬病控制项目的未来经济效益。在这项研究中，使用数学模拟模型来确定从 2006 年的索引病例开始浣熊狂犬病的潜在传播情况，并计算了人类暴露后预防（PEP）、动物检测和人类暴露调查的发病率。效益被计算为由于控制而减少的人类 PEP、动物检测和人类暴露调查的潜在节省，范围从 4700 万美元到 5300 万美元。项目成本情景基于总支出的预测，范围从 3300 万美元到 4900 万美元。大约一半的模型情景显示出了经济效益，其中最大的效益成本比来自于未来项目成本的降低。
