前列腺素D2、F2α和E1对兔输卵管自发收缩影响的比较。

Comparison of the effects of prostaglandins D2, F2alpha and E1 on spontaneous contractions of rabbit oviduct.

作者信息

Heesch C M, Valenzuela G, Hodgson B J

出版信息

Prostaglandins. 1977 Aug;14(2):279-82. doi: 10.1016/0090-6980(77)90173-3.

Abstract

The effects of PGD2, PGF2alpha and PGE1 were studied on the circular muscle of post-ovulatory rabbit oviducts in vitro. PGE1 inhibited spontaneous contractile activity. Lower concentrations of PGD2 and PGF2alpha were stimulatory and higher concentrations were inhibitory. Since PGD2 may be produced in the oviduct, any hypothesis concerning the role of prostaglandins in the control of oviductal motility and ovum transport should include PGD2 as well as PGFs and PGEs.

摘要

研究了前列腺素D2（PGD2）、前列腺素F2α（PGF2α）和前列腺素E1（PGE1）对排卵后兔输卵管环形肌的体外作用。PGE1抑制自发收缩活动。较低浓度的PGD2和PGF2α具有刺激作用，而较高浓度则具有抑制作用。由于PGD2可能在输卵管中产生，任何关于前列腺素在控制输卵管运动和卵子运输中作用的假说都应包括PGD2以及前列腺素F类和前列腺素E类。