Brock G, Hsu G L, Nunes L, von Heyden B, Lue T F
Department of Urology, University of California School of Medicine, San Francisco, USA.
J Urol. 1997 Jan;157(1):276-81.
We studied the fine architecture of the tunica albuginea of the penis.
The study included 6 human male cadavers and 10 surgical patients (5 with Peyronie's disease and 5 with normal penile anatomy).
The tunica albuginea of the corpora cavernosa is a bi-layered structure with multiple sub layers. Inner layer bundles support and contain the cavernous tissue and are oriented circularly. Radiating from this layer are intracavernous pillars acting as struts, which augment the septum and provide essential support to the erectile tissue. Outer layer bundles are oriented longitudinally. These fibers extend from the glans penis to the proximal crura, where they insert into the inferior pubic ramus. There are no outer layer fibers between the 5 and 7 o'clock positions. Elastic fibers normally form an irregularly latticed network on which collagen fibers rest. In Peyronie's disease the well ordered appearance of the collagen layers is lost: excessive deposits of collagen, disordered elastic fibers and fibrin are found within the region of the plaque.
The normal 3-dimensional structure of the tunica affords great flexibility, rigidity and tissue strength to the penis, which are lost consequent to structural changes in Peyronie's disease.
我们研究了阴茎白膜的精细结构。
该研究纳入了6具男性尸体及10例手术患者（5例佩罗尼氏病患者和5例阴茎解剖结构正常者）。
海绵体白膜是一种具有多个亚层的双层结构。内层束状结构支撑并包含海绵体组织，呈环形排列。从该层向外辐射出作为支柱的海绵体内柱状结构，其增强了中隔并为勃起组织提供重要支撑。外层束状结构呈纵向排列。这些纤维从阴茎头延伸至近端脚，在此处它们插入耻骨下支。在5点至7点位置之间没有外层纤维。弹性纤维通常形成一个不规则的格子状网络，胶原纤维附着其上。在佩罗尼氏病中，胶原层的有序外观丧失：在斑块区域内发现胶原过度沉积、弹性纤维紊乱和纤维蛋白。
白膜的正常三维结构赋予阴茎极大的柔韧性、刚性和组织强度，而在佩罗尼氏病中，由于结构改变，这些特性丧失。
