• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene.

作者信息

Altomare D A, Kozak C A, Sonoda G, Testa J R

机构信息

Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

出版信息

Cytogenet Cell Genet. 1996;74(4):248-51. doi: 10.1159/000134426.

DOI:10.1159/000134426
PMID:8976376
Abstract

We previously reported the cloning of a murine cDNA encoding the protein-serine/threonine kinase Akt2, and we used this clone to map the Akt2 gene to mouse chromosome (MMU) 7B1 by fluorescence in situ hybridization. We now have cloned and partially sequenced a mouse Akt2 pseudogene. An analysis of two sets of multilocus crosses revealed that the Akt2 gene is closely linked to the Cyp2a locus in proximal MMU7. The Akt2 pseudogene was mapped to proximal MMU11 by both multilocus mapping and fluorescence in situ hybridization.

摘要

相似文献

1
Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene.
Cytogenet Cell Genet. 1996;74(4):248-51. doi: 10.1159/000134426.
2
Cloning, chromosomal localization and expression analysis of the mouse Akt2 oncogene.小鼠Akt2癌基因的克隆、染色体定位及表达分析。
Oncogene. 1995 Sep 21;11(6):1055-60.
3
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.AKT2是一种假定的癌基因，编码蛋白丝氨酸/苏氨酸激酶亚家族的一个成员，在人类卵巢癌中发生扩增。
Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9267-71. doi: 10.1073/pnas.89.19.9267.
4
Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization.通过荧光原位杂交将编码Akt/蛋白激酶B家族成员的AKT3映射到人类和啮齿动物染色体上。
Cytogenet Cell Genet. 2000;88(1-2):38-40. doi: 10.1159/000015481.
5
Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer.在人类胰腺癌中分离19号染色体q13.1 - q13.2区域扩增的DNA序列，包括AKT2基因座
Biochem Biophys Res Commun. 1996 Aug 23;225(3):968-74. doi: 10.1006/bbrc.1996.1280.
6
Cloning and genomic mapping of the mouse matrin 3 gene and its pseudogenes.小鼠核基质蛋白3基因及其假基因的克隆与基因组定位
Cytogenet Cell Genet. 1998;81(3-4):194-8. doi: 10.1159/000015028.
7
Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes.小鼠巨噬细胞移动抑制因子（MIF）的基因组克隆以及人和小鼠表达基因与九个小鼠假基因的遗传定位。
Genomics. 1995 Jun 10;27(3):405-11. doi: 10.1006/geno.1995.1070.
8
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.
Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3636-41. doi: 10.1073/pnas.93.8.3636.
9
Chromosome mapping of the human genes encoding the MAP kinase kinase MEK1 (MAP2K1) to 15q21 and MEK2 (MAP2K2) to 7q32.将编码丝裂原活化蛋白激酶激酶MEK1（MAP2K1）的人类基因定位于15q21，以及将MEK2（MAP2K2）定位于7q32的染色体图谱分析。
Cytogenet Cell Genet. 2000;88(3-4):249-52. doi: 10.1159/000015530.
10
Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2.鉴定出一个位于3号染色体3p14.3 - 21.1区域的基因APPL，它编码一种与癌蛋白丝氨酸/苏氨酸激酶AKT2相互作用的衔接分子。
Oncogene. 1999 Sep 2;18(35):4891-8. doi: 10.1038/sj.onc.1203080.