Davis I J, Grim C, Dwyer K, Nicholson L, Dwyer J
Charles R. Drew University, College of Allied Health, Center for the Advancement of Allied Health Education, Los Angeles, California, USA.
J Natl Med Assoc. 1996 Dec;88(12):774-8.
This longitudinal trial investigated the effects of calcium supplementation on the mean 24-hour blood pressure in African-American adolescents. Subjects were self-identified African-American adolescents from a high school in a suburb of Los Angeles, California. The subjects were randomly placed in a placebo or treatment group (placebo versus 1.5 g of calcium/day x 4 weeks). Follow-up mean 24-hour ambulatory blood pressure (ABP) for both the treatment and control groups was lower than the baseline mean 24-hour ABP. In the treatment group, there was a decrease of 2.2 mm Hg in the mean systolic blood pressure and 0.7 mm Hg in the diastolic blood pressure. Relative to the placebo group, the net change in ABP was -1.7 mm Hg for systolic blood pressure and -0.5 mm Hg for the diastolic blood pressure. There was no statistically significant effect of calcium supplementation on the 24-hour mean ABP. The net effect of supplementation on ABP during waking and sleeping hours also was not significant.
这项纵向试验研究了补钙对非裔美国青少年24小时平均血压的影响。研究对象是来自加利福尼亚州洛杉矶郊区一所高中的自我认定为非裔美国青少年。这些受试者被随机分为安慰剂组或治疗组（安慰剂组与每天1.5克钙×4周的治疗组）。治疗组和对照组的随访24小时动态血压（ABP）均低于基线24小时ABP。治疗组的平均收缩压下降了2.2毫米汞柱，舒张压下降了0.7毫米汞柱。相对于安慰剂组，ABP的净变化为收缩压-1.7毫米汞柱，舒张压-0.5毫米汞柱。补钙对24小时平均ABP没有统计学上的显著影响。补充剂对清醒和睡眠时间ABP的净影响也不显著。
