Donegan W L
Department of Surgery, Sinai Samaritan Medical Center, Milwaukee, Wisconsin, USA.
CA Cancer J Clin. 1997 Jan-Feb;47(1):28-51. doi: 10.3322/canjclin.47.1.28.
Interest in prognostic factors for breast cancer has been stimulated by the success of systemic adjuvant therapy for early-stage operable disease. Patients destined for recurrence can be selected for systemic adjuvant therapy, while patients not likely to recur can be spared the morbidity of unnecessary treatment. The number of tumor-related features available for prognosis has grown impressively in recent years. The purpose of this article is to review tumor-related biologic factors and relate them to prognosis and treatment objectives.
早期可手术乳腺癌的全身辅助治疗取得成功，激发了人们对乳腺癌预后因素的兴趣。有可能复发的患者可选择全身辅助治疗，而不太可能复发的患者则可避免不必要治疗带来的并发症。近年来，可用于预后评估的肿瘤相关特征数量显著增加。本文旨在综述肿瘤相关生物学因素，并将它们与预后及治疗目标联系起来。
