Portney G L, Roth A M
Am J Ophthalmol. 1977 Jul;84(1):98-103. doi: 10.1016/0002-9394(77)90332-4.
A 51-year-old woman had optic disk cupping from optic nerve compression by an intracranial aneurysm. Slit-lamp stereoscopic examination of the living eye immediately post mortem revealed an optic cup vertically oral, elongated superiorly, and indistinguishable from disk changes seen early in glaucoma. The histopathological changes differed from those in glaucoma by showing no glial atrophy. Instead, the cupping was caused by loss of axons in the prelaminar region of the nerve head and collapse of glial columns.
一名51岁女性因颅内动脉瘤压迫视神经导致视盘杯状凹陷。死后立即对活体眼进行裂隙灯立体检查,发现视杯垂直开口,向上拉长,与青光眼早期所见的视盘变化难以区分。组织病理学变化与青光眼不同,未显示神经胶质萎缩。相反,杯状凹陷是由神经乳头层前区轴突丧失和神经胶质柱塌陷引起的。