Spaide R F, Campeas L, Haas A, Yannuzzi L A, Fisher Y L, Guyer D R, Slakter J S, Sorenson J A, Orlock D A
LuEsther Mertz Retina Research Laboratory, New York, NY, USA.
Ophthalmology. 1996 Dec;103(12):2070-9; discussion 2079-80. doi: 10.1016/s0161-6420(96)30386-2.
The purpose of the study is to investigate the demographic characteristics and clinical findings of central serous chorioretinopathy (CSC).
This study examined a consecutive series of 130 patients with CSC seen over an 18-month period.
The mean age of the patients when examined was 51 years, and the male-to-female ratio was 2.6:1.0. A total of 62 patients were older than 50 years of age when first examined. Although the patients shared some clinical and angiographic similarities, the older patients had a lower mean visual acuity and were more likely to have diffuse retinal pigment epitheliopathy, bilateral involvement, and secondary choroidal neovascularization than were the younger patients. With ophthalmoscopic and angiographic examination results, it was possible to differentiate CSC in older adults from choroidal neovascularization.
This study expands the clinical concept of CSC. The male-to-female ratio was much lower, and the range of ages of the patients was much greater than in previous studies. Disease manifestations in older adults differed somewhat from those seen in younger adults. In older patients, CSC can be distinguished from other exudative maculopathies, particularly that of choroidal neovascularization secondary to age-related macular degeneration.
本研究旨在调查中心性浆液性脉络膜视网膜病变（CSC）的人口统计学特征和临床发现。
本研究对18个月期间连续就诊的130例CSC患者进行了检查。
接受检查时患者的平均年龄为51岁，男女比例为2.6:1.0。共有62例患者首次检查时年龄超过50岁。尽管患者在临床和血管造影方面有一些相似之处，但老年患者的平均视力较低，与年轻患者相比，更易出现弥漫性视网膜色素上皮病变、双侧受累及继发性脉络膜新生血管。通过眼底镜和血管造影检查结果，能够将老年成人的CSC与脉络膜新生血管区分开来。
本研究扩展了CSC的临床概念。男女比例远低于以往研究，患者年龄范围比以往研究大得多。老年成人的疾病表现与年轻成人有所不同。在老年患者中，CSC可与其他渗出性黄斑病变相鉴别，尤其是年龄相关性黄斑变性继发的脉络膜新生血管病变。
