某综合医院耐头孢西丁肺炎克雷伯菌暴发的研究
Study of an outbreak of cefoxitin-resistant Klebsiella pneumoniae in a general hospital.
作者信息
Gazouli M, Kaufmann M E, Tzelepi E, Dimopoulou H, Paniara O, Tzouvelekis L S
机构信息
Department of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
出版信息
J Clin Microbiol. 1997 Feb;35(2):508-10. doi: 10.1128/jcm.35.2.508-510.1997.
Abstract
During a 3-month period, six Klebsiella pneumoniae isolates resistant to cefoxitin and penicillin-inhibitor combinations were derived from patients in the intensive care unit of a hospital in Athens, Greece. Enterobacterial repetitive intergenic consensus PCR and pulsed-field gel electrophoresis provided evidence of the clonal origin of the isolates. Conventional techniques and ribotyping were inadequate in proving that the isolates were related. Resistance was due to a plasmidic class C beta-lactamase.
摘要
在3个月的时间里，从希腊雅典一家医院的重症监护病房患者中分离出6株对头孢西丁和青霉素抑制剂联合耐药的肺炎克雷伯菌。肠道细菌重复基因间共识PCR和脉冲场凝胶电泳为这些分离株的克隆起源提供了证据。传统技术和核糖体分型不足以证明这些分离株之间存在关联。耐药性是由一种质粒介导的C类β-内酰胺酶引起的。
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