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类风湿性关节炎合并颈椎脊髓病患者功能评分系统的开发。

Development of a functional scoring system for rheumatoid arthritis patients with cervical myelopathy.

作者信息

Casey A T, Bland J M, Crockard H A

机构信息

Department of Surgical Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom.

出版信息

Ann Rheum Dis. 1996 Dec;55(12):901-6. doi: 10.1136/ard.55.12.901.

Abstract

OBJECTIVE

To be able to measure disability objectively in rheumatoid arthritis complicated by cervical myelopathy.

METHODS

The responses to the Stanford health assessment questionnaire disability index were recorded from 250 consecutive patients (group 1) referred to our unit for spinal surgery. Using principal components analysis the questionnaire was reduced from 20 questions to 10 questions. In the second part of the study, the results of the questionnaire for those patients undergoing surgery from the original group of 250 patients were analysed with respect to outcome.

RESULTS

The reduction in the number of questions results in no significant loss of information, reliability (internal consistency Cronbach's alpha = 0.968) or sensitivity. The new scale, the myelopathy disability index, measures only one dimension (Eigen value 6.97) and may be more finely tuned to the measurement of disability in these myelopathic patients. When administered to the 194 patients undergoing cervical spine (group 2) surgery the myelopathy disability index was an accurate predictor of neurological and functional outcome, as well as survival following surgery (P < 0.0001).

CONCLUSIONS

The myelopathy disability index provides a much needed objective and reliable means of assessing disability in patients with rheumatoid involvement of the cervical spine and also in predicting outcome following surgical intervention. It also provides information for both the patient and surgeon alike, on what to realistically expect from surgery. Its adoption should facilitate comparisons between different forms of surgical intervention.

摘要

目的

能够客观测量类风湿性关节炎合并颈椎脊髓病患者的残疾情况。

方法

记录了连续250例因脊柱手术转诊至我院的患者(第1组)对斯坦福健康评估问卷残疾指数的回答。通过主成分分析,问卷从20个问题减少到10个问题。在研究的第二部分,分析了最初250例患者中接受手术患者的问卷结果与手术结局的关系。

结果

问题数量的减少并未导致信息显著丢失、可靠性(内部一致性Cronbach's alpha = 0.968)或敏感性降低。新的量表,即脊髓病残疾指数,仅测量一个维度(特征值6.97),可能更精确地用于测量这些脊髓病患者的残疾情况。当应用于194例接受颈椎手术的患者(第2组)时,脊髓病残疾指数是神经和功能结局以及术后生存率的准确预测指标(P < 0.0001)。

结论

脊髓病残疾指数为评估颈椎类风湿性病变患者的残疾情况以及预测手术干预后的结局提供了一种急需的客观且可靠的方法。它还为患者和外科医生提供了关于手术实际预期效果的信息。采用该指数应有助于不同形式手术干预之间的比较。

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