Challa V R, Jona J
Dermatologica. 1977;155(4):206-9. doi: 10.1159/000251000.
A case of painful eccrine angiomatous hamartoma of the wrist in a 10-year-old girl is presented. It was located in the reticular dermis and contained abnormal tubules resembling eccrine secretory coils and thin vascular channels dispersed in the collagenous tissue of the dermis. Some eccrine ducts showed dilatation. The noteworthy features of this case were the absence of hyperhidrosis over the lesion, and the presence of focal neural infiltration by the tubular structures. Electron microscopy showed mostly clear cells and occasional dark cells lining the tubular structures. This case supports the theory of abnormal induction of heterotypic dependency with resultant malformation of adnexal as well as mesenchymal elements.
本文报告一例10岁女孩腕部疼痛性小汗腺血管瘤样错构瘤。病变位于网状真皮层，包含类似小汗腺分泌蟠管的异常小管以及散在于真皮胶原组织中的细小血管通道。部分小汗腺导管扩张。该病例的显著特征是病变部位无多汗症，且管状结构存在局灶性神经浸润。电子显微镜检查显示，管状结构内衬大多为透明细胞，偶尔可见暗细胞。该病例支持异型依赖性异常诱导导致附属器及间充质成分畸形的理论。
