Kam P C, Tan K H
Department of Anaesthesia, Royal Prince Alfred Hospital, Camperdown, N.S.W., Australia.
Anaesthesia. 1996 Dec;51(12):1133-8. doi: 10.1111/j.1365-2044.1996.tb15050.x.
The mechanisms of pruritus, an unpleasant irritation on the skin that provokes an urge to scratch, are reviewed. Whilst symptomatic treatment is only partially effective, antihistamines remain the first choice of treatment. However, recent novel treatment using opiate antagonists, propofol (subhypnotic doses) and serotonin antagonists offer attractive alternatives.
本文综述了瘙痒（一种引起搔抓冲动的皮肤不适感）的发病机制。虽然对症治疗仅部分有效，但抗组胺药仍是首选治疗方法。然而，最近使用阿片类拮抗剂、丙泊酚（亚催眠剂量）和5-羟色胺拮抗剂的新型治疗方法提供了有吸引力的替代方案。
