蜱传脑炎：在急性期可能是一种致命疾病。从死后脑组织中进行蜱传脑炎病毒RNA的PCR扩增。

Tick-borne encephalitis: possibly a fatal disease in its acute stage. PCR amplification of TBE RNA from postmortem brain tissue.

作者信息

Tomazic J, Poljak M, Popovic P, Maticic M, Beovic B, Avsic-Zupanc T, Lotric S, Jereb M, Pikelj F, Gale N

机构信息

Dept. of Infectious Diseases, University Medical Centre Ljubljana, Slovenia.

出版信息

Infection. 1997 Jan-Feb;25(1):41-3. doi: 10.1007/BF02113507.

DOI:10.1007/BF02113507

PMID:9039538

Abstract

Tick-borne encephalitis has occurred regularly in Europe since it was first diagnosed in 1931 by Schneider. The mortality rate of patients with this disease is 1-2%. Death usually occurs in the acute stage of illness. A case report of a 28-year-old patient from Slovenia, who died shortly after the onset of tick-borne encephalitis, is described. The clinical course of disease, results of serological tests, neuropathological findings and polymerase chain reaction amplification of parts of viral genome from postmortem brain tissues are presented.

摘要

自1931年施奈德首次诊断出蜱传脑炎以来，这种疾病在欧洲定期出现。该疾病患者的死亡率为1%-2%。死亡通常发生在疾病的急性期。本文描述了一名来自斯洛文尼亚的28岁患者的病例报告，该患者在蜱传脑炎发病后不久死亡。文中介绍了疾病的临床病程、血清学检测结果、神经病理学发现以及死后脑组织中病毒基因组部分区域的聚合酶链反应扩增结果。